Introduction

BEMPIDOC EZ 180/10 combination medication plays a crucial role. Formulated with Bempedoic Acid (180mg) and Ezetimibe (10mg), this medication is designed to help lower cholesterol levels effectively. Elevated cholesterol, particularly low-density lipoprotein (LDL) cholesterol, is a significant risk factor for cardiovascular diseases, including heart attacks and strokes. The synergistic action of these two components not only targets cholesterol levels but also offers a unique approach to managing hyperlipidemia. This article delves into the uses, benefits, mechanism of action, dosage, side effects, and pricing of BEMPIDOC EZ 180/10, providing a comprehensive understanding of this essential medication.

What is BEMPIDOC EZ 180/10?

BEMPIDOC EZ 180/10 is a prescription medication that combines two powerful agents—Bempedoic Acid and Ezetimibe.

• Bempedoic Acid is a novel agent that inhibits ATP-citrate lyase, an enzyme involved in cholesterol synthesis in the liver.
• Ezetimibe works by reducing cholesterol absorption in the intestines.

Together, these components work to effectively lower LDL cholesterol and total cholesterol levels in patients with hyperlipidemia.

Key Ingredients

Bempedoic Acid (180mg)

Bempedoic Acid is a member of a new class of cholesterol-lowering agents known as ATP-citrate lyase inhibitors. This medication specifically targets cholesterol production in the liver.

Mechanism of Action

Bempedoic Acid acts by inhibiting ATP-citrate lyase, leading to a reduction in the synthesis of cholesterol and triglycerides. By decreasing the hepatic cholesterol pool, it promotes the upregulation of hepatic LDL receptors, which enhances the clearance of LDL from the bloodstream.

Key Benefits of Bempedoic Acid

• Lowers LDL cholesterol levels: Clinical trials have demonstrated that Bempedoic Acid significantly reduces LDL cholesterol levels, making it an effective treatment for patients who have not achieved their target cholesterol levels with statins or other medications.
• No risk of muscle-related side effects: Unlike statins, Bempedoic Acid has a lower incidence of muscle-related side effects, making it a suitable option for patients who are statin-intolerant.

Ezetimibe (10mg)

Ezetimibe is a well-established medication that selectively inhibits the intestinal absorption of cholesterol.

Mechanism of Action

Ezetimibe works by blocking the Niemann-Pick C1-like 1 (NPC1L1) protein in the intestinal wall, which is responsible for the absorption of dietary and biliary cholesterol. This action results in decreased cholesterol delivery to the liver and promotes further LDL receptor upregulation.

Key Benefits of Ezetimibe

• Effective in lowering LDL cholesterol: Ezetimibe can reduce LDL cholesterol levels by about 15-20% when used alone. When combined with Bempedoic Acid, the cholesterol-lowering effect is enhanced.
• Complementary action: The combination of Ezetimibe with Bempedoic Acid provides a multi-faceted approach to lipid management, targeting both hepatic cholesterol synthesis and intestinal absorption.

Uses of BEMPIDOC EZ 180/10

BEMPIDOC EZ 180/10 is primarily indicated for:

1. Hyperlipidemia: It is prescribed for patients with primary hyperlipidemia or mixed dyslipidemia who require additional LDL cholesterol reduction, especially those who are statin-intolerant or who have not achieved adequate control with statins alone.

2. Cardiovascular Risk Reduction: By lowering LDL cholesterol levels, BEMPIDOC EZ 180/10 plays a significant role in reducing the risk of cardiovascular events, including heart attacks and strokes.

Dosage

The typical dosage of BEMPIDOC EZ 180/10 is one tablet taken orally once daily. It can be taken with or without food, making it convenient for patients to incorporate into their daily routines.

Recommended Dosage Adjustment

• Initial Dosage: For patients who are not currently on lipid-lowering therapy, the usual starting dose is 180mg of Bempedoic Acid and 10mg of Ezetimibe.
• Renal Impairment: Dosage adjustments may be necessary for patients with moderate to severe renal impairment. It's essential to consult a healthcare provider for specific recommendations.

How Does It Work?

BEMPIDOC EZ 180/10 works synergistically to lower LDL cholesterol levels.

• Bempedoic Acid decreases cholesterol synthesis in the liver, while Ezetimibe reduces the absorption of cholesterol from the diet.
• This dual mechanism results in a more significant reduction in LDL cholesterol compared to either medication alone, providing an effective treatment option for patients struggling to manage their cholesterol levels.

Side Effects

As with any medication, BEMPIDOC EZ 180/10 may cause side effects. However, many patients tolerate it well. Common side effects include:

• Muscle-related symptoms: While Bempedoic Acid is associated with fewer muscle-related side effects compared to statins, some patients may still experience muscle pain or cramps.
• Gastrointestinal issues: Patients may report symptoms such as diarrhea, nausea, or abdominal pain, primarily due to Ezetimibe.
• Elevated liver enzymes: Routine monitoring of liver function is recommended, as both components may cause increases in liver enzymes in some patients.

Serious Side Effects

Though rare, patients should be aware of serious side effects that may occur, including:

• Allergic reactions: Symptoms may include rash, itching, or swelling.
• Severe muscle problems: Such as rhabdomyolysis, though this is more common with statins than with Bempedoic Acid.

Precautions

Before starting BEMPIDOC EZ 180/10, patients should inform their healthcare provider of:

• Medical history: Especially any history of liver disease or muscle disorders.
• Other medications: Some drugs may interact with Bempedoic Acid or Ezetimibe, impacting their efficacy or increasing the risk of side effects.

Pricing

The price of BEMPIDOC EZ 180/10 can vary based on factors such as location, pharmacy, and insurance coverage. On average, a month's supply may range from ₹1,500 to ₹2,500 in India. Patients are encouraged to check with their local pharmacies for exact pricing and explore options for generic alternatives if cost is a concern.

Conclusion

BEMPIDOC EZ 180/10 offers a valuable solution for individuals struggling with high LDL cholesterol levels. With its unique formulation of Bempedoic Acid (180mg) and Ezetimibe (10mg), it provides a dual approach to lipid management, effectively lowering cholesterol while minimizing side effects. As cardiovascular diseases remain a leading health concern globally, medications like BEMPIDOC EZ 180/10 play a critical role in preventive healthcare. Always consult a healthcare provider for personalized advice and to determine the best treatment options for your individual health needs. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, Sterisonline  ,  Sterisindia and Sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 7877551268, 7849827488

BUY NOW