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Comprehensive Guide to Mesalamine ER 400mg: Benefits, Dosage, and Safety

Aug 10, 2024

MESALMILE 400 

Mesalamine ER (400mg)

Introduction

Mesalamine ER 400mg, known as MESALMILE 400, is an extended-release formulation primarily used to treat inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. This medication belongs to the aminosalicylates class, which works by reducing inflammation directly in the colon. For patients suffering from chronic inflammation of the intestines, Mesalamine ER 400mg offers a therapeutic option that provides sustained relief, ensuring that the medication is steadily released over time, directly targeting the affected area.

Uses of Mesalamine ER 400mg

Mesalamine ER 400mg is specifically formulated to manage and treat conditions related to inflammatory bowel disease (IBD). Its primary uses include:

  1. Ulcerative Colitis: This chronic condition causes inflammation and ulcers in the colon and rectum. Mesalamine ER 400mg helps reduce inflammation, alleviate symptoms like diarrhea and rectal bleeding, and maintain remission, preventing flare-ups.
  2. Crohn's Disease: While more commonly used for ulcerative colitis, Mesalamine ER 400mg is also sometimes prescribed for Crohn's disease, especially when the inflammation is localized in the colon. It helps in controlling symptoms and maintaining periods of remission.
  3. Maintenance Therapy: Mesalamine ER 400mg is also effective as a long-term maintenance therapy, helping patients stay symptom-free over extended periods. The extended-release formulation ensures that the medication remains effective throughout the day, reducing the need for frequent dosing.

Dosage of Mesalamine ER 400mg

The dosage of Mesalamine ER 400mg varies depending on the severity of the condition, the patient’s medical history, and their response to treatment. It is crucial to follow a healthcare provider’s instructions when taking this medication. Typically, the dosage is as follows:

  • For Active Ulcerative Colitis: The recommended dose is 2.4 to 4.8 grams per day, divided into smaller doses. Patients are often prescribed 800mg twice a day or 400mg three times a day, depending on the severity of the condition.
  • For Maintenance of Remission: Once remission is achieved, the dosage is usually reduced. Most patients are advised to take 1.6 grams per day, which could be 400mg taken four times a day or as directed by a healthcare provider.
  • Special Considerations: Dosage adjustments may be necessary for patients with kidney or liver impairment, or for those who experience side effects. It is essential to take the medication consistently, preferably at the same time each day, with or without food.

Side Effects of Mesalamine ER 400mg

Like all medications, Mesalamine ER 400mg can cause side effects, although not everyone experiences them. Common side effects include:

  • Gastrointestinal Issues: Some patients may experience stomach cramps, nausea, or diarrhea. These symptoms are usually mild and tend to resolve as the body adjusts to the medication.
  • Headache: A common side effect reported by patients taking Mesalamine ER 400mg. It is generally mild and can be managed with over-the-counter pain relievers if necessary.
  • Respiratory Symptoms: Although rare, some individuals may develop respiratory issues such as shortness of breath or chest pain. If these occur, it is crucial to seek medical attention immediately.
  • Kidney and Liver Effects: Long-term use of Mesalamine ER 400mg may affect kidney or liver function. Regular monitoring by a healthcare provider is recommended to ensure the medication does not cause significant harm.
  • Allergic Reactions: Although uncommon, allergic reactions can occur. Symptoms may include rash, itching, swelling, severe dizziness, or trouble breathing. Immediate medical attention is required if any of these symptoms arise.

Price of Mesalamine ER 400mg in India

The cost of MESALMILE 400, or Mesalamine ER 400mg, varies depending on the manufacturer, location, and pharmacy. On average, the price for a strip of 10 tablets in India ranges from ₹150 to ₹300. Prices may fluctuate, and it is advisable to check with local pharmacies or online platforms for the most accurate and up-to-date pricing. Additionally, patients might find discounts or generic versions available, which can help reduce costs.

Conclusion

Mesalamine ER 400mg is a vital medication for managing and maintaining remission in patients with inflammatory bowel diseases like ulcerative colitis and Crohn's disease. Its extended-release formulation ensures continuous medication delivery, helping to control inflammation and prevent flare-ups. While generally well-tolerated, it is essential for patients to be aware of potential side effects and to communicate regularly with their healthcare providers. By following prescribed dosages and monitoring their condition, patients can achieve significant improvements in their quality of life. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. Based in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, underscoring its commitment to quality and safety. Sterispharma is dedicated to providing high-quality drugs at affordable prices across India, strictly adhering to WHO guidelines. Sterispharma offers the convenience of an online pharmacy, enabling customers to easily purchase medicines and benefit from home delivery. The company's mission is to supply a wide array of healthcare products to meet the diverse needs of the medical community. Whether it's advanced treatments, medications for rare conditions, or essential health necessities, Sterispharma strives to serve the broad demands of the healthcare industry. If you need medicine then you can order it on these two websites sterisonline and sterispharma  Order Now Sterispharma's extensive product lineup includes treatments for various health areas such as Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information:

Email: info@sterispharma.com / contact@sterispharma.com

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