MAYORANDIL 5

Nicorandil (5mg)

Introduction

Nicorandil 5mg, marketed under the brand name Mayorandil 5, is a potent vasodilatory drug commonly prescribed for the management of angina pectoris. Angina pectoris, characterized by chest pain due to reduced blood flow to the heart, is a common symptom of coronary artery disease. Nicorandil works by relaxing and widening blood vessels, thereby improving blood flow and reducing the workload on the heart. This article provides an in-depth exploration of Nicorandil 5mg, covering its uses, dosage, side effects, price in India, and additional pertinent information.

Uses

Nicorandil 5mg is primarily used for the prevention and long-term treatment of angina pectoris. By dilating both the coronary arteries and veins, it helps to enhance the oxygen supply to the heart muscle, thereby alleviating chest pain and reducing the frequency of angina attacks. Moreover, Nicorandil is beneficial in patients who are intolerant or unresponsive to conventional anti-anginal medications such as beta-blockers and calcium channel blockers.

In addition to angina management, Nicorandil has shown efficacy in the treatment of chronic heart failure and has been studied for its potential benefits in improving outcomes following percutaneous coronary intervention (PCI).

Dosage

The standard starting dose of Nicorandil 5mg is typically administered twice daily, once in the morning and once in the evening. Based on the patient's response and clinical condition, the dosage may be gradually increased by the healthcare provider, with the usual maintenance dose ranging from 10mg to 20mg twice daily.

It is essential to follow the prescribed dosage regimen strictly and not to adjust the dose without consulting a healthcare professional. Nicorandil should be swallowed whole with a sufficient amount of water and can be taken with or without food. In case of a missed dose, it should be taken as soon as remembered unless it is almost time for the next scheduled dose, in which case the missed dose should be skipped.

Side Effects

Nicorandil is generally well-tolerated; however, like all medications, it may cause side effects in some individuals. Common side effects include headaches, dizziness, and flushing, which are typically mild and transient. Gastrointestinal disturbances such as nausea, vomiting, and abdominal pain may also occur.

In rare instances, Nicorandil can cause more severe side effects such as ulcers in the mouth, stomach, or intestines, which may necessitate discontinuation of the drug. Hypotension (low blood pressure), palpitations, and fainting are other potential adverse effects, particularly in patients who are prone to these conditions.

Patients should seek immediate medical attention if they experience any signs of a serious allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing.

Price

In India, the price of Nicorandil 5mg varies depending on the manufacturer and the pharmacy. On average, a strip of 10 tablets of Mayorandil 5 may cost around ₹50 to ₹100. Prices can differ significantly based on the brand and the region of purchase. It is advisable to check with multiple pharmacies or online platforms to find the best price available.

Additional Information

• Mechanism of Action: Nicorandil acts through dual mechanisms – it is a potassium channel opener and a nitrate-like compound. This dual action helps in dilating both the large coronary arteries and the smaller resistance vessels, improving oxygen supply to the heart muscle and reducing myocardial oxygen demand.

• Precautions: Patients with a history of peptic ulcers, hypotension, or those taking other vasodilators should use Nicorandil with caution. Regular monitoring by a healthcare provider is recommended to manage potential adverse effects and interactions with other medications.

• Drug Interactions: Nicorandil may interact with other drugs, particularly those used to treat hypertension and heart conditions. It is crucial to inform the healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid harmful interactions.

• Storage: Nicorandil should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets.

Conclusion

Nicorandil 5mg (Mayorandil 5) is an effective medication for managing angina pectoris and other heart-related conditions. Its dual action mechanism makes it a valuable option for patients who do not respond well to other anti-anginal drugs. While generally well-tolerated, it is essential to be aware of potential side effects and drug interactions. Always follow the prescribed dosage regimen and consult a healthcare provider for any concerns or if severe side effects occur. With proper usage and monitoring, Nicorandil can significantly improve the quality of life for individuals suffering from chronic angina. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. Based in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, underscoring its commitment to quality and safety. Sterispharma is dedicated to providing high-quality drugs at affordable prices across India, strictly adhering to WHO guidelines. Sterispharma offers the convenience of an online pharmacy, enabling customers to easily purchase medicines and benefit from home delivery. The company's mission is to supply a wide array of healthcare products to meet the diverse needs of the medical community. Whether it's advanced treatments, medications for rare conditions, or essential health necessities, Sterispharma strives to serve the broad demands of the healthcare industry. If you need medicine then you can order it on these two websites sterisonline and sterispharma  Order Now Sterispharma's extensive product lineup includes treatments for various health areas such as Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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