DABIGATREX 75 

Dabigatran etexilate (75mg)

DABIGATREX 75, is a potent oral anticoagulant prescribed primarily for the prevention and treatment of thromboembolic disorders. As a direct thrombin inhibitor, Dabigatran Etexilate plays a crucial role in reducing the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation. Additionally, it is used to prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) following surgery. In this article, we will explore the uses, dosage, side effects, price, and other essential details about DABIGATREX 75 to provide a comprehensive understanding of this medication.

What is DABIGATREX 75?

DABIGATREX 75 contains Dabigatran Etexilate, a prodrug that is rapidly converted into its active form, Dabigatran, in the body. Dabigatran acts by directly inhibiting thrombin, a key enzyme in the coagulation process. By inhibiting thrombin, Dabigatran prevents the formation of blood clots, thereby reducing the risk of stroke and other thromboembolic events. DABIGATREX 75 is available in a 75mg dosage, making it suitable for patients who require lower doses of anticoagulant therapy, such as those with renal impairment or elderly patients.

Uses of DABIGATREX 75

• Prevention of Stroke and Systemic Embolism: DABIGATREX 75 is prescribed to patients with non-valvular atrial fibrillation to reduce the risk of stroke and systemic embolism. Atrial fibrillation increases the likelihood of blood clots forming in the heart, which can then travel to the brain or other parts of the body, leading to serious complications.
• Treatment and Prevention of Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE): DVT occurs when a blood clot forms in a deep vein, typically in the legs. If the clot dislodges and travels to the lungs, it can cause a pulmonary embolism, a potentially life-threatening condition. DABIGATREX 75 is effective in treating existing clots and preventing the formation of new clots.
• Post-Surgical Prophylaxis: After certain types of surgery, particularly hip or knee replacement surgeries, there is an increased risk of developing blood clots. DABIGATREX 75 is used as a preventive measure to reduce this risk and ensure a safer recovery.

Dosage and Administration

• Standard Dosage: The standard dosage of DABIGATREX 75 is one capsule taken orally, twice a day. The exact dosage may vary depending on the patient's medical condition, renal function, and response to treatment.
• Administration: DABIGATREX 75 should be taken with a full glass of water, with or without food. It is essential to swallow the capsule whole without breaking, chewing, or opening it, as this can affect the medication's efficacy.
• Adjustments: For patients with moderate renal impairment or those at increased risk of bleeding, the dosage may need to be adjusted. It is crucial to follow the prescribing doctor's instructions carefully and attend regular follow-up appointments to monitor the medication's effectiveness and adjust the dose if necessary.

Side Effects

While DABIGATREX 75 is generally well-tolerated, some patients may experience side effects. It is essential to be aware of these potential side effects and consult a healthcare professional if any of them occur:

• Common Side Effects:
  • Gastrointestinal Issues: Nausea, stomach pain, indigestion, and diarrhea are common gastrointestinal side effects associated with DABIGATREX 75.
  • Bleeding: Since Dabigatran is an anticoagulant, an increased risk of bleeding is a significant concern. This may manifest as bruising, nosebleeds, gum bleeding, or more severe bleeding complications.
  • Allergic Reactions: Some patients may develop allergic reactions such as rash, itching, or swelling, particularly of the face, lips, or throat.
• Serious Side Effects:
  • Severe Bleeding: In rare cases, DABIGATREX 75 can cause severe bleeding in the gastrointestinal tract, brain, or other areas, leading to life-threatening conditions.
  • Kidney Issues: Although rare, some patients may experience kidney-related side effects, particularly if they have pre-existing renal conditions.

Price of DABIGATREX 75

The price of DABIGATREX 75 can vary depending on the brand, pharmacy, and location. On average, a pack of 10 capsules may cost between ₹500 and ₹700 in India. Prices may fluctuate based on discounts, offers, and local availability. It is advisable to purchase DABIGATREX 75 from a reputable pharmacy to ensure the authenticity and quality of the medication.

Safety Information and Precautions

• Medical History: Before starting DABIGATREX 75, inform your healthcare provider about your complete medical history, especially if you have a history of bleeding disorders, kidney problems, or recent surgeries.
• Drug Interactions: DABIGATREX 75 may interact with other medications, including anticoagulants, antiplatelet drugs, and NSAIDs. Discuss all medications and supplements you are taking with your doctor to avoid potential interactions.
• Pregnancy and Breastfeeding: DABIGATREX 75 should be used with caution during pregnancy and breastfeeding. Consult your healthcare provider to weigh the potential risks and benefits before using this medication.
• Missed Dose: If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for the missed one.

Conclusion

DABIGATREX 75 is an essential medication for patients at risk of thromboembolic disorders, providing effective prevention and treatment of conditions such as stroke, DVT, and PE. With its role as a direct thrombin inhibitor, it significantly reduces the risk of blood clots while maintaining a manageable safety profile. While there are potential side effects, particularly concerning bleeding, the benefits of DABIGATREX 75 often outweigh the risks for those in need of anticoagulant therapy. It is crucial to use this medication under the supervision of a healthcare provider, adhere to the prescribed dosage, and attend regular check-ups to ensure optimal outcomes. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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