FRUSIP PLUS 20 

Furosemide (20 mg) & Spironolactone (50mg)

FRUSIP PLUS 20 is a potent combination medication that merges the effects of two well-known diuretics: Furosemide (20 mg) and Spironolactone (50 mg). This formulation is primarily used to manage conditions related to fluid retention (edema) and hypertension. The synergy of Furosemide and Spironolactone in this drug provides a balanced approach to removing excess fluids from the body while maintaining essential potassium levels, making it an effective treatment for patients with heart failure, liver cirrhosis, and certain kidney disorders.

How FRUSIP PLUS 20 Works
FRUSIP PLUS 20 harnesses the diuretic powers of both Furosemide and Spironolactone to combat fluid retention:

• Furosemide (20 mg): A loop diuretic that works by inhibiting the reabsorption of sodium and chloride in the kidneys, specifically in the loop of Henle. This process leads to the increased excretion of water, sodium, chloride, magnesium, and calcium, which helps in reducing fluid buildup in tissues and the circulatory system.

• Spironolactone (50 mg): A potassium-sparing diuretic that functions as an aldosterone antagonist. It blocks the action of aldosterone, a hormone responsible for increasing sodium and water retention while conserving potassium. This mechanism helps in preventing hypokalemia (low potassium levels), a common side effect of other diuretics like Furosemide.

Uses of FRUSIP PLUS 20
FRUSIP PLUS 20 is prescribed for a variety of conditions where fluid retention is an issue:

1. Edema: The drug is widely used to treat edema associated with congestive heart failure, liver cirrhosis, and nephrotic syndrome. By reducing the excess fluid in the body, it helps alleviate swelling in the legs, ankles, and abdomen.

2. Hypertension: The combination of Furosemide and Spironolactone is effective in lowering blood pressure, particularly in cases of resistant hypertension, where conventional treatments have failed.

3. Heart Failure: In patients with heart failure, this medication helps reduce the workload on the heart by removing excess fluid, thereby improving symptoms like shortness of breath and swelling.

4. Liver Cirrhosis: For patients with liver cirrhosis, FRUSIP PLUS 20 helps manage fluid accumulation in the abdomen (ascites) by promoting the excretion of excess sodium and water.

5. Chronic Kidney Disease: This combination is sometimes used in the management of fluid retention in patients with chronic kidney disease, although careful monitoring is required.

Dosage and Administration
The dosage of FRUSIP PLUS 20 should be tailored to the individual patient's needs, depending on the severity of the condition and the patient’s response to the medication. It is typically taken once daily, with or without food. However, in some cases, a twice-daily regimen may be recommended.

• Initial Dose: For adults, the typical starting dose is one tablet of FRUSIP PLUS 20 per day. Depending on the patient’s response, the dose may be adjusted by the healthcare provider.

• Maintenance Dose: The maintenance dose is individualized based on the patient's needs and the clinical response. In some cases, the dosage may be increased or decreased.

• Missed Dose: If a dose is missed, it should be taken as soon as possible. However, if it’s close to the time of the next dose, skip the missed dose and resume the regular dosing schedule. Do not double the dose to catch up.

Side Effects of FRUSIP PLUS 20
Like all medications, FRUSIP PLUS 20 may cause side effects. It is essential to be aware of these potential adverse effects to manage them effectively.

• Common Side Effects:
  • Dizziness or lightheadedness, especially when standing up quickly
  • Headache
  • Dehydration
  • Electrolyte imbalance, including hyperkalemia (high potassium levels) and hyponatremia (low sodium levels)
  • Gastrointestinal disturbances such as nausea, vomiting, or diarrhea
• Serious Side Effects:
  • Severe dehydration and electrolyte disturbances lead to confusion, muscle weakness, or irregular heartbeats
  • Kidney dysfunction
  • Allergic reactions, including rash, itching, or swelling, especially of the face, tongue, or throat
  • Severe abdominal pain, dark urine, or jaundice, indicating liver problems
  • Unusual bleeding or bruising

Patients are advised to seek immediate medical attention if they experience any severe side effects.

Precautions and Warnings
Before starting FRUSIP PLUS 20, it is important to consider several precautions to ensure safe and effective use:

• Kidney Function: This medication should be used with caution in patients with impaired kidney function, as both Furosemide and Spironolactone can affect renal function.

• Liver Function: Patients with liver disease should be closely monitored while taking this medication, as it may exacerbate liver conditions.

• Electrolyte Monitoring: Regular monitoring of electrolytes, particularly potassium and sodium levels, is crucial to prevent imbalances that could lead to serious complications.

• Pregnancy and Breastfeeding: FRUSIP PLUS 20 is generally not recommended during pregnancy or breastfeeding unless deemed absolutely necessary by a healthcare provider.

• Drug Interactions: This medication can interact with other drugs, including blood pressure medications, NSAIDs, lithium, and certain antibiotics. Patients should inform their healthcare provider of all medications they are taking.

The price of FRUSIP PLUS 20 in India
The price of FRUSIP PLUS 20 can vary depending on the pharmacy and location. On average, a strip of 10 tablets may cost between INR 50 to INR 150. Prices may fluctuate, and it is advisable to check with local pharmacies for the most accurate and current pricing.

Conclusion
FRUSIP PLUS 20, combining Furosemide (20 mg) and Spironolactone (50 mg), offers a powerful solution for managing fluid retention and hypertension. Its dual-action approach not only effectively removes excess fluid but also preserves potassium levels, reducing the risk of complications associated with other diuretics. However, like all medications, it must be used under the guidance of a healthcare provider, with regular monitoring to ensure safety and efficacy. Whether it’s for treating edema, heart failure, or hypertension, FRUSIP PLUS 20 remains a valuable option in the therapeutic arsenal, providing relief to patients with conditions that demand effective diuretic therapy. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

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