MESALMILE 500 PR

Mesalamine DR (500mg)

Introduction

Mesalamine DR (500mg), also known as delayed-release mesalamine, is a widely used medication in the management of inflammatory bowel diseases (IBD), including ulcerative colitis and Crohn's disease. This medication is sold under the name MESALMILE 500 PR. This medication belongs to a class of drugs known as aminosalicylates, which work by reducing inflammation in the colon. The delayed-release formulation ensures that the active ingredient, mesalamine, is released gradually in the intestines, where it is most needed. This helps to minimize side effects and maximize therapeutic benefits.

Mesalamine DR 500mg is prescribed to both adults and children to help manage symptoms such as abdominal pain, diarrhea, and rectal bleeding. It is also used to maintain remission in patients with ulcerative colitis, thereby preventing flare-ups. This comprehensive guide will cover everything you need to know about Mesalamine DR 500mg, including its uses, dosage, side effects, pricing in India, and more.

Uses of Mesalamine DR 500mg

Mesalamine DR 500mg is primarily used to treat and manage inflammatory bowel diseases (IBD). The drug's anti-inflammatory properties are particularly effective in treating the inflammation associated with ulcerative colitis and Crohn's disease. In patients with ulcerative colitis, Mesalamine DR helps to reduce symptoms such as abdominal pain, diarrhea, and rectal bleeding. It is also used to maintain remission in patients with ulcerative colitis, preventing flare-ups and helping patients manage their condition more effectively.

In addition to treating active symptoms, Mesalamine DR 500mg is also prescribed as a maintenance therapy to help patients stay in remission. This is particularly important for patients with chronic ulcerative colitis, as it can help to prevent the need for more aggressive treatments, such as corticosteroids or surgery.

How Mesalamine DR 500mg Works

Mesalamine DR 500mg works by inhibiting the production of certain chemicals in the body that cause inflammation. The delayed-release formulation of the drug ensures that the active ingredient is released gradually in the intestines, where it is most needed. This helps to reduce inflammation in the colon, which is the primary cause of symptoms in patients with IBD.

The drug is thought to work by inhibiting the production of prostaglandins and leukotrienes, which are chemicals that play a key role in the inflammatory process. By reducing the levels of these chemicals in the body, Mesalamine DR helps to reduce inflammation in the colon, which in turn helps to alleviate symptoms such as abdominal pain, diarrhea, and rectal bleeding.

Dosage and Administration of Mesalamine DR 500mg

The dosage of Mesalamine DR 500mg varies depending on the condition being treated, the severity of the symptoms, and the patient's age and overall health. It is important to follow your healthcare provider's instructions carefully when taking this medication.

For Adults:

The typical starting dose for adults with active ulcerative colitis is two 500mg tablets taken three times daily, for a total of 3 grams per day. Once the symptoms are under control, the dosage may be reduced to one 500mg tablet taken three times daily for maintenance therapy. Some patients may require a higher or lower dose depending on their response to the medication.

For Children:

The dosage for children with ulcerative colitis is typically based on the child's weight. The starting dose is usually 20-30 mg/kg of body weight per day, divided into two or three doses. The dosage may be adjusted based on the child's response to the medication.

How to Take Mesalamine DR 500mg:

Mesalamine DR 500mg tablets should be swallowed whole, with or without food. It is important not to crush, chew, or break the tablets, as this can interfere with the delayed-release formulation and reduce the effectiveness of the medication. If you have difficulty swallowing tablets, talk to your healthcare provider about alternative formulations of mesalamine that may be easier to take.

Missed Dose:

If you miss a dose of Mesalamine DR 500mg, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once to make up for a missed dose.

Overdose:

If you accidentally take too much Mesalamine DR 500mg, contact your healthcare provider or seek emergency medical attention right away. Symptoms of an overdose may include nausea, vomiting, diarrhea, and stomach pain.

Side Effects of Mesalamine DR 500mg

Like all medications, Mesalamine DR 500mg can cause side effects, although not everyone experiences them. Most side effects are mild and go away on their own, but some can be more serious and may require medical attention.

Common Side Effects:

• Nausea
• Headache
• Stomach pain
• Diarrhea
• Rash

Serious Side Effects:

In rare cases, Mesalamine DR 500mg can cause more serious side effects, including kidney problems, liver problems, and blood disorders. Contact your healthcare provider right away if you experience any of the following symptoms:

• Severe stomach pain or cramping
• Blood in your stool
• Yellowing of the skin or eyes (jaundice)
• Dark urine
• Unusual bruising or bleeding

Allergic Reactions:

Some people may be allergic to mesalamine. If you experience symptoms of an allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat, seek emergency medical attention right away.

Price of Mesalamine DR 500mg in India

The price of Mesalamine DR 500mg can vary depending on the brand, the quantity purchased, and the pharmacy where it is purchased. On average, the cost of a month's supply of Mesalamine DR 500mg in India ranges from ₹1,500 to ₹2,500. Some brands may be more expensive, while others may offer discounts or generic versions at a lower cost.

It is important to note that prices can vary widely depending on the pharmacy and location, so it may be worth shopping around or using an online pharmacy to find the best price. Additionally, some patients may be eligible for government or insurance programs that can help cover the cost of the medication.

Precautions and Interactions

Before taking Mesalamine DR 500mg, it is important to inform your healthcare provider about any other medications you are taking, including prescription and over-the-counter drugs, vitamins, and supplements. Some medications can interact with mesalamine, increasing the risk of side effects or reducing the effectiveness of the drug.

Kidney and Liver Function:

Mesalamine DR 500mg can affect kidney and liver function, so it is important to have regular blood tests to monitor these organs while taking the medication. If you have a history of kidney or liver problems, your healthcare provider may need to adjust your dosage or monitor you more closely.

Pregnancy and Breastfeeding:

Mesalamine DR 500mg is generally considered safe to use during pregnancy, but it is important to discuss the risks and benefits with your healthcare provider. If you are breastfeeding, it is important to inform your healthcare provider, as mesalamine can pass into breast milk.

Other Conditions:

If you have a history of heart disease, stomach ulcers, or other gastrointestinal conditions, it is important to inform your healthcare provider before taking Mesalamine DR 500mg.

Conclusion

Mesalamine DR 500mg is a highly effective medication for the treatment and management of inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. Its delayed-release formulation ensures that the active ingredient is released gradually in the intestines, where it is most needed, helping to reduce inflammation and alleviate symptoms. While most side effects are mild, it is important to be aware of the potential for more serious side effects and to inform your healthcare provider of any other medications or conditions that may interact with mesalamine. Steris Healthcare Pvt Ltd, founded by a group of expert professionals in the pharmaceutical industry in February 2018, operates as Sterispharma. Based in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, underscoring its commitment to quality and safety. Sterispharma is dedicated to providing high-quality drugs at affordable prices across India, strictly adhering to WHO guidelines. Sterispharma offers the convenience of an online pharmacy, enabling customers to easily purchase medicines and benefit from home delivery. The company's mission is to supply a wide array of healthcare products to meet the diverse needs of the medical community. Whether it's advanced treatments, medications for rare conditions, or essential health necessities, Sterispharma strives to serve the broad demands of the healthcare industry. If you need medicine then you can order it on these two websites sterisonline and sterispharma  Order Now Sterispharma's extensive product lineup includes treatments for various health areas such as Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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