OXIFYLINE PR 400 

Pentoxifylline (400mg)

OXIFYLINE PR 400, containing 400mg of Pentoxifylline, is a well-regarded medication used primarily for its vasodilatory and anti-inflammatory properties. It is commonly prescribed to manage conditions related to poor blood circulation and peripheral vascular diseases. This article provides an in-depth look at OXIFYLINE PR 400, including its uses, dosage, side effects, and other essential details.

What is Pentoxifylline?

Pentoxifylline is a xanthine derivative that improves blood flow by decreasing the viscosity of blood and enhancing the flexibility of red blood cells. This results in better oxygen delivery to tissues and improved overall circulation. OXIFYLINE PR 400 is a sustained-release formulation of Pentoxifylline, designed to provide a controlled and prolonged release of the medication.

How Does OXIFYLINE PR 400 Work?

OXIFYLINE PR 400 works by inhibiting phosphodiesterase, an enzyme involved in the breakdown of cyclic AMP. This inhibition leads to increased levels of cyclic AMP, which results in the relaxation of blood vessels and improved blood flow. Additionally, Pentoxifylline decreases the aggregation of platelets and enhances the deformability of red blood cells, further improving circulation and oxygen delivery to tissues.

Uses of OXIFYLINE PR 400

1. Peripheral Vascular Disease (PVD): OXIFYLINE PR 400 is commonly prescribed to manage symptoms of PVD, such as intermittent claudication, which causes pain and cramping in the legs due to insufficient blood flow.
2. Chronic Venous Insufficiency (CVI): It is used to treat CVI, a condition where the veins in the legs cannot efficiently return blood to the heart, leading to symptoms like swelling and ulcers.
3. Diabetic Neuropathy: OXIFYLINE PR 400 can be beneficial in managing diabetic neuropathy by improving blood flow and reducing the risk of complications associated with diabetes.
4. Post-Surgical Recovery: It may also be prescribed to enhance recovery after certain types of surgery, particularly those involving vascular procedures.

Dosage and Administration

The typical dosage of OXIFYLINE PR 400 is one tablet taken three times daily, preferably with meals to reduce gastrointestinal discomfort. It is important to follow the dosage prescribed by a healthcare provider and not to exceed the recommended amount. The sustained-release formulation ensures a gradual release of Pentoxifylline, providing long-lasting effects with fewer side effects compared to immediate-release formulations.

Potential Side Effects

Like all medications, OXIFYLINE PR 400 can cause side effects. Common side effects include:

• Gastrointestinal Problems: It's possible to experience diarrhea, vomiting, nausea, and stomach pain. Taking the drug with food could lessen these side effects.
• Headache: The drug may cause headaches in certain persons.
• Dizziness: Especially when getting up fast, dizziness or lightheadedness may strike.

Serious side effects are rare but may include:

• Severe Allergic Reactions: Symptoms may include rash, itching, swelling, or difficulty breathing. Immediate medical attention is required if these occur.
• Bleeding or Bruising: Since Pentoxifylline can affect platelet function, unusual bleeding or bruising should be reported to a healthcare provider.

Interactions with Other Medications

OXIFYLINE PR 400 may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects. Notable interactions include:

• Anticoagulants: The risk of bleeding may be increased when Pentoxifylline is used with blood thinners like warfarin.
• Antidiabetic Medications: Careful monitoring is required when used with medications for diabetes, as Pentoxifylline can affect blood sugar levels.
• Other Vasodilators: Combining with other vasodilatory drugs may enhance the effects, potentially leading to excessive lowering of blood pressure.

Precautions and Warnings

Before starting OXIFYLINE PR 400, inform your healthcare provider of any existing medical conditions, particularly:

• Liver or Kidney Issues: Dosage adjustments may be necessary for individuals with liver or kidney impairment.
• Heart Conditions: Patients with heart conditions should use OXIFYLINE PR 400 with caution.
• Pregnancy and Breastfeeding: The safety of Pentoxifylline during pregnancy and breastfeeding has not been well-established. 

Price and Availability

OXIFYLINE PR 400 is available by prescription and can be obtained from pharmacies. In India, the cost of a month’s supply typically ranges between ₹600 to ₹800. It's advisable to check with local pharmacies for the most accurate pricing and availability.

Conclusion

OXIFYLINE PR 400, with its active ingredient Pentoxifylline, offers a valuable option for managing conditions related to poor blood circulation and peripheral vascular diseases. By improving blood flow and reducing inflammation, it helps alleviate symptoms and improve quality of life for patients. As with any medication, it is essential to use OXIFYLINE PR 400 under the guidance of a healthcare professional, adhere to prescribed dosages, and be aware of potential side effects and interactions. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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