OXIFYLINE PR 400 

Pentoxifylline (400mg)

OXIFYLINE PR 400 is a pharmaceutical product containing Pentoxifylline (400mg), a medication primarily used to improve blood flow in patients with circulation problems. This extended-release tablet is particularly effective in treating conditions such as intermittent claudication and other peripheral artery diseases. By enhancing the flow of blood, OXIFYLINE PR 400 helps alleviate symptoms like muscle pain and cramps that occur during exercise.

What is Pentoxifylline?

Pentoxifylline is a xanthine derivative that functions as a hemorheologic agent. It works by improving the flexibility of red blood cells and decreasing blood viscosity, thus enhancing microcirculation and oxygen delivery to tissues. This medication is commonly prescribed for patients suffering from peripheral vascular diseases, particularly when lifestyle modifications and other treatments have not yielded sufficient results.

How OXIFYLINE PR 400 Works

OXIFYLINE PR 400 works through several mechanisms:

1. Improving Blood Flow: Pentoxifylline increases the deformability of red blood cells, which helps them pass through narrow blood vessels more easily.
2. Reducing Blood Viscosity: By lowering the thickness of the blood, Pentoxifylline makes it easier for blood to circulate through the body.
3. Anti-inflammatory Effects: Pentoxifylline has mild anti-inflammatory properties, which can help reduce inflammation in blood vessels and improve blood flow.

Uses of OXIFYLINE PR 400

Peripheral Artery Disease (PAD)

One of the primary uses of OXIFYLINE PR 400 is in the treatment of Peripheral Artery Disease (PAD). PAD is characterized by narrowed arteries, which reduce blood flow to the limbs, leading to pain and discomfort. Pentoxifylline helps improve blood flow, thereby reducing symptoms such as leg pain while walking (intermittent claudication).

Cerebrovascular Disorders

Pentoxifylline can also be used to manage certain cerebrovascular disorders. By improving blood flow to the brain, it may help alleviate symptoms associated with conditions such as stroke and transient ischemic attacks (TIAs).

Diabetic Neuropathy

In patients with diabetic neuropathy, improved blood flow can help manage symptoms such as pain, tingling, and numbness in the extremities. Pentoxifylline's ability to enhance microcirculation is beneficial in these cases.

Other Uses

OXIFYLINE PR 400 may also be prescribed for other conditions where improved blood flow can be beneficial, including chronic venous insufficiency, and sometimes in cases of sickle cell disease.

Dosage and Administration

Recommended Dosage

The typical dosage for OXIFYLINE PR 400 is one tablet taken orally three times a day. It is crucial to follow the prescribed dosage and not to alter the dose without consulting a healthcare professional.

How to Take OXIFYLINE PR 400

• With Food: To minimize gastrointestinal side effects, it is recommended to take OXIFYLINE PR 400 with meals.
• Swallow Whole: The tablets should be swallowed whole and not crushed or chewed, as they are extended-release tablets designed to release the medication slowly over time.

Missed Dose

If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next dose. In such cases, skip the missed dose and resume the regular dosing schedule. Do not double up on doses to make up for the missed one.

Side Effects

Common Side Effects

Some common side effects of OXIFYLINE PR 400 include:

• Nausea
• Vomiting
• Dizziness
• Headache
• Bloating

Serious Side Effects

Although rare, some serious side effects may occur. If any of the following symptoms are experienced, medical attention should be sought immediately:

• Chest pain
• Severe dizziness
• Irregular heartbeat
• Persistent nausea or vomiting
• Signs of an allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing)

Precautions and Warnings

Medical History

Before starting OXIFYLINE PR 400, it is essential to inform the healthcare provider about any medical history, particularly:

• Bleeding disorders
• Peptic ulcer disease
• Recent surgery
• History of stroke

Drug Interactions

Pentoxifylline can interact with several other medications, including:

• Anticoagulants (e.g., warfarin)
• Antiplatelet drugs (e.g., clopidogrel)
• Blood pressure medications
• Theophylline

Inform the healthcare provider about all medications and supplements currently being taken to avoid potential interactions.

Pregnancy and Breastfeeding

The safety of Pentoxifylline during pregnancy and breastfeeding has not been fully established. It should only be used if the potential benefits justify the potential risks to the fetus or infant. Consult a healthcare provider before use.

Storage and Handling

Storage

Store OXIFYLINE PR 400 at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets.

Handling

Do not use the medication if the seal is broken or if the tablets show any signs of damage. Dispose of any unused or expired medication properly, according to local regulations.

Price and Availability

OXIFYLINE PR 400 is available at most pharmacies. The price may vary depending on the pharmacy and location. It is advisable to check with local pharmacies or online retailers for the best price options.

Conclusion

OXIFYLINE PR 400 (Pentoxifylline 400mg) is a valuable medication for individuals suffering from peripheral vascular diseases and other circulation-related conditions. By improving blood flow and reducing blood viscosity, it helps alleviate symptoms such as muscle pain and cramps, enhancing the quality of life for many patients. As with any medication, it is essential to follow the prescribed dosage and consult a healthcare professional for any concerns or potential interactions with other medications. Always ensure proper storage and handling of the medication to maintain its efficacy and safety. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

For further information

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp: 7877551268, 7849827488

BUY NOW