OXIFYLINE PR 400 

Pentoxifylline (400mg)

Oxifyline PR 400, is a medication renowned for its vasodilatory properties, primarily used to improve blood flow. It belongs to the methylxanthine class of drugs and is particularly effective in treating conditions where blood circulation is impaired.

Mechanism of Action

The primary mechanism of Pentoxifylline involves inhibiting phosphodiesterase and adenosine uptake, which results in increased levels of cyclic adenosine monophosphate (cAMP) and adenosine. These biochemical changes lead to vasodilation and improved blood flow in various parts of the body, particularly in peripheral vessels.

Medical Uses

1. Peripheral Vascular Disease (PVD):

• Pentoxifylline is widely prescribed for individuals suffering from PVD, including conditions like intermittent claudication. By enhancing blood circulation to the limbs, it helps alleviate symptoms such as pain and cramping.

2. Chronic Venous Insufficiency (CVI):

• In cases of CVI, where veins fail to adequately pump blood back to the heart, Pentoxifylline aids in improving venous tone and reducing symptoms like swelling and skin changes.

3. Cerebrovascular Disease:

• Studies suggest that Pentoxifylline may have neuroprotective effects and could potentially benefit patients recovering from stroke by promoting cerebral blood flow.

4. Other Applications:

• Beyond vascular conditions, Pentoxifylline has shown promise in treating certain dermatological conditions and as an adjunct therapy in some inflammatory disorders.

Dosage and Administration

Typically, Pentoxifylline is administered orally, with a usual dosage of 400mg taken three times daily. The extended-release formulation, such as Oxifyline PR 400, allows for twice-daily dosing, enhancing patient compliance and convenience.

Side Effects

While generally well-tolerated, Pentoxifylline may cause mild to moderate side effects, including nausea, dizziness, and gastrointestinal disturbances. Serious adverse effects are rare but can include allergic reactions and arrhythmias in susceptible individuals.

Cost and Availability

Pentoxifylline, under the brand Oxifyline PR 400, is widely available in pharmacies and through medical providers. The cost can vary depending on the region and healthcare provider, but generic forms are often more affordable.

Conclusion

In conclusion, Pentoxifylline, marketed as Oxifyline PR 400, is a valuable medication for enhancing blood flow and treating various vascular and inflammatory conditions. Its mechanism of action, coupled with manageable side effects and convenient dosing, makes it a preferred choice for many healthcare professionals.  Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488  

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