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Pirfenidone 200mg Guide: Uses, Dosage, Side Effects, and Price

Jul 26, 2024

Introduction

PIRFENOID 200 is a prescription medication containing Pirfenidone (200mg), widely used to treat Idiopathic Pulmonary Fibrosis (IPF). Pirfenidone is an anti-fibrotic and anti-inflammatory agent that helps slow down lung tissue scarring and improves respiratory function in individuals suffering from IPF.

This article provides a detailed overview of PIRFENOID 200, covering its key benefits, uses, dosage, side effects, precautions, and more.

What is Pirfenidone (200mg)?

Pirfenidone (200mg) is an orally administered medication that helps reduce lung fibrosis in patients with IPF. It works by targeting the pathways that lead to tissue scarring and inflammation, thus slowing down disease progression. Pirfenidone is known for its ability to modulate pro-inflammatory cytokines and inhibit fibroblast proliferation.

Key Benefits of PIRFENOID 200

  • Slows Down Lung Fibrosis: Helps in reducing the progression of Idiopathic Pulmonary Fibrosis by inhibiting fibrotic pathways.

  • Improves Breathing Capacity: Aids in maintaining lung function and reducing breathlessness.

  • Anti-Inflammatory Properties: Reduces lung inflammation and prevents excessive scarring.

  • Enhances Quality of Life: Helps patients maintain daily activities with improved respiratory function.

  • Delays Disease Progression: Extends survival rates and reduces the need for oxygen therapy in severe cases.

How PIRFENOID 200 Works?

Pirfenidone (200mg) works by inhibiting fibroblast growth factors (FGFs), tumor necrosis factor-alpha (TNF-α), and transforming growth factor-beta (TGF-β). These are key proteins involved in fibrosis and inflammation. By blocking these pathways, Pirfenidone effectively reduces the thickening and scarring of lung tissues, allowing better oxygen exchange.

Dosage & Administration

Recommended Dosage

The typical dosage of PIRFENOID 200 for Idiopathic Pulmonary Fibrosis (IPF) follows an escalation schedule to minimize side effects:

  • Week 1: 200mg three times a day

  • Week 2: 400mg three times a day

  • Week 3 and onwards: 600mg three times a day (Maximum dose: 1800mg/day)

How to Take PIRFENOID 200?

  • Take with food to reduce stomach irritation.

  • Swallow the tablet whole with a glass of water.

  • Do not crush or chew the tablet.

  • Take at the same time every day for better results.

Possible Side Effects

Like all medications, PIRFENOID 200 may cause some side effects, although not everyone experiences them. The common side effects include:

Common Side Effects:

  • Nausea and Vomiting

  • Diarrhea

  • Skin Rash (Especially after sun exposure)

  • Fatigue

  • Loss of Appetite

  • Dizziness

Serious Side Effects (Seek Medical Attention):

  • Liver Dysfunction (Yellowing of skin/eyes, dark urine)

  • Severe Skin Reactions (Blistering, peeling, or itching)

  • Chest Pain or Shortness of Breath

  • Extreme Sensitivity to Sunlight (Photosensitivity reactions)

If any severe reactions occur, discontinue the medication and consult your doctor immediately.

Precautions & Warnings

Who Should Avoid PIRFENOID 200?

  • Patients with severe liver or kidney disease.

  • Individuals allergic to Pirfenidone or any of its ingredients.

  • Pregnant or breastfeeding women (Consult a doctor before use).

  • Those with a history of photosensitivity reactions.

Precautionary Measures

  • Regular Liver Function Tests (LFTs) are recommended to monitor liver health.

  • Avoid Alcohol as it may worsen liver toxicity.

  • Use Sunscreen & Protective Clothing to prevent photosensitivity reactions.

  • Inform Your Doctor about all other medications to avoid potential drug interactions.

Drug Interactions

Pirfenidone (200mg) may interact with other medications, affecting its efficacy or increasing side effects. Some notable drug interactions include:

  • Ciprofloxacin & Fluconazole: May increase Pirfenidone levels, leading to toxicity.

  • Omeprazole & Esomeprazole: May reduce Pirfenidone levels, decreasing its effectiveness.

  • Smoking: Reduces the bioavailability of Pirfenidone, making the treatment less effective.

Always inform your healthcare provider about any medications or supplements you are taking before starting PIRFENOID 200.

Price & Availability in India

The cost of PIRFENOID 200 varies based on the brand and pharmacy. In India, the approximate price ranges between ₹800 – ₹1500 per pack, depending on the manufacturer and location.

You can purchase PIRFENOID 200 from registered pharmacies with a valid prescription. Online pharmacies also offer discounts and doorstep delivery options.

FAQs About PIRFENOID 200

1. How long should I take PIRFENOID 200?

The treatment duration depends on the progression of Idiopathic Pulmonary Fibrosis and your doctor’s recommendation. Long-term usage is often required to manage the condition effectively.

2. Can PIRFENOID 200 cure Idiopathic Pulmonary Fibrosis?

No, PIRFENOID 200 does not cure IPF, but it significantly slows down the disease progression and improves lung function.

3. What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it is close to the next dose, skip the missed one. Do not double the dose.

4. Is PIRFENOID 200 safe for long-term use?

Yes, but regular monitoring of liver function and side effects is essential for safe long-term use.

5. Can I stop taking PIRFENOID 200 abruptly?

No, stopping Pirfenidone suddenly may worsen IPF symptoms. Always consult your doctor before discontinuing.

Conclusion

PIRFENOID 200, containing Pirfenidone (200mg), is a vital medication for managing Idiopathic Pulmonary Fibrosis (IPF). It effectively slows down lung fibrosis, improves breathing, and enhances the quality of life for IPF patients. However, like all medications, it comes with potential side effects and requires medical supervision for safe usage.

If you or a loved one has IPF, consult a healthcare provider to determine whether PIRFENOID 200 is the right choice. Always adhere to prescribed dosage and precautions for optimal benefits.

For more details, consult a pulmonologist or visit a licensed pharmacy to obtain PIRFENOID 200 with a valid prescription.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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