PIRFENOID 400

Pirfenidone (400mg)

PIRFENOID 400 is a medication that contains Pirfenidone ( 400mg), an antifibrotic agent primarily used to treat idiopathic pulmonary fibrosis (IPF). IPF is a chronic, progressive lung disease characterized by the thickening and scarring of lung tissue, leading to severe breathing difficulties and decreased oxygen transfer to the blood. PIRFENOID 400 helps manage this condition by slowing the progression of fibrosis, thereby improving lung function and enhancing the quality of life for patients.

Uses of PIRFENOID 400

Primary Indication: Idiopathic Pulmonary Fibrosis (IPF)

Pirfenidone is specifically approved for the treatment of idiopathic pulmonary fibrosis. It works by inhibiting the production of collagen and cytokines that contribute to fibrosis, thus reducing the progression of the disease. Clinical studies have shown that Pirfenidone can significantly slow the decline in lung function and improve exercise capacity in patients with IPF.

Potential Off-Label Uses

While the primary use of PIRFENOID 400 is for IPF, there is ongoing research into its effectiveness for other fibrotic conditions such as liver fibrosis and kidney fibrosis. However, these uses are not yet widely approved and should only be considered under the guidance of a healthcare professional.

Dosage and Administration

Recommended Dosage

The typical dosage of PIRFENOID 400 for adults is one tablet (400mg) three times a day. The dosage may be adjusted based on the patient's response to treatment and the occurrence of any side effects.

Administration Guidelines

• With Food: To minimize gastrointestinal side effects, PIRFENOID 400 should be taken with food.
• Regular Schedule: Taking the medication at the same times each day helps maintain stable drug levels in the body.

Potential Side Effects

Common Side Effects

• Gastrointestinal Issues: Nausea, vomiting, diarrhea, and stomach pain are common side effects that often diminish over time.
• Skin Reactions: Rash, itching, and photosensitivity (increased sensitivity to sunlight) may occur.
• Fatigue: Some patients may experience tiredness or general weakness.

Serious Side Effects

• Liver Function Changes: Pirfenidone can affect liver enzymes, necessitating regular monitoring of liver function. Symptoms of liver issues include yellowing of the skin or eyes (jaundice), dark urine, and severe fatigue.
• Allergic Reactions: Although rare, allergic reactions such as hives, difficulty breathing, and swelling of the face or throat require immediate medical attention.

Drug Interactions

Important Interactions

• CYP1A2 Inhibitors: Medications that inhibit the enzyme CYP1A2, such as fluvoxamine and ciprofloxacin, can increase pirfenidone levels in the blood, potentially leading to increased side effects.
• Smoking: Smoking can induce CYP1A2, decreasing the effectiveness of PIRFENOID 400. 

Precautions and Warnings

Liver Monitoring

Before starting PIRFENOID 400, patients should undergo liver function tests, and these tests should be repeated regularly during treatment to detect any potential liver damage early.

Photosensitivity

Due to the risk of photosensitivity reactions, patients should avoid prolonged exposure to sunlight and use adequate sun protection measures, including sunscreen and protective clothing.

Conclusion

PIRFENOID 400 (Pirfenidone 400mg) is an essential medication for managing idiopathic pulmonary fibrosis, offering hope to patients by slowing disease progression and improving quality of life.   Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488  

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