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Rabiprazole 20 + Levosulpride 75 mg SR

Jul 07, 2022

Introduction

RABISTRUM LS is a pharmaceutical product that combines two active ingredients: Levosulpride (75mg SR) and Rabeprazole (20mg). It is primarily used to manage gastrointestinal conditions and disorders related to the stomach, such as acid reflux, gastritis, and irritable bowel syndrome (IBS). Each component of RABISTRUM LS plays a critical role in providing relief and restoring balance to the digestive system.

  • Levosulpride is an atypical antipsychotic medication with prokinetic and antiemetic properties. It helps improve gastrointestinal motility and reduce symptoms like nausea and bloating.

  • Rabeprazole is a proton pump inhibitor (PPI) that reduces stomach acid production, providing relief from acid-related gastrointestinal disorders, such as GERD (Gastroesophageal Reflux Disease) and peptic ulcers.

Together, these two ingredients offer a synergistic effect in treating a variety of stomach and digestive-related issues.

Composition

  1. Levosulpride (75mg SR):

    • Mechanism of Action: Levosulpride is a selective dopamine D2 receptor antagonist that improves gastrointestinal motility. It works by enhancing the movement of the stomach and intestines, which helps to alleviate symptoms of bloating, nausea, and delayed gastric emptying. The sustained-release formulation (SR) allows for a prolonged effect, ensuring that the medication is effective over an extended period of time.

    • Prokinetic Properties: Levosulpride stimulates the motility of the stomach and intestines, promoting smoother digestion and preventing the feeling of fullness or discomfort that can arise from slow digestion.

  2. Rabeprazole (20mg):

    • Mechanism of Action: Rabeprazole is a proton pump inhibitor (PPI) that reduces the production of stomach acid by blocking the proton pumps in the stomach lining. This reduction in acid production helps treat conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and gastritis.

    • Acid Suppression: By lowering stomach acid levels, Rabeprazole helps prevent acid reflux, ulcers, and inflammation, providing relief from associated symptoms like heartburn, chest pain, and regurgitation.

Benefits of RABISTRUM LS

RABISTRUM LS offers multiple benefits, especially for individuals with gastrointestinal disorders:

  1. Improved Gastric Motility:

    • The inclusion of Levosulpride in the formulation helps improve stomach motility. This is beneficial for individuals suffering from conditions like gastroparesis (delayed gastric emptying) and IBS. It helps to reduce bloating, nausea, and abdominal discomfort by enhancing the movement of food through the digestive tract.

  2. Acid Reflux and GERD Relief:

    • The Rabeprazole component of RABISTRUM LS effectively suppresses gastric acid secretion, alleviating symptoms of acid reflux and GERD. By reducing the acid levels in the stomach, Rabeprazole helps prevent the irritation of the esophagus and alleviates heartburn and regurgitation.

  3. Protection Against Stomach Ulcers:

    • By lowering the production of stomach acid, Rabeprazole helps in healing and preventing peptic ulcers, which are often exacerbated by high acid levels in the stomach. RABISTRUM LS can be particularly beneficial for individuals with ulcers caused by Helicobacter pylori infection or those taking non-steroidal anti-inflammatory drugs (NSAIDs).

  4. Enhanced Digestion:

    • Levosulpride helps to improve the motility of the intestines and stomach, ensuring food moves through the digestive system more efficiently. This enhances digestion and absorption of nutrients and reduces the feelings of fullness or discomfort after meals.

  5. Anti-nausea Effect:

    • Levosulpride also has antiemetic (anti-nausea) properties, making RABISTRUM LS useful for individuals who experience nausea and vomiting, particularly in conditions such as IBS, gastritis, or post-surgical recovery.

Key Features and Ingredients

  1. Levosulpride (75mg SR):

    • Prokinetic Action: Levosulpride promotes gastrointestinal motility by enhancing the movement of the stomach and intestines, improving overall digestion and reducing bloating and discomfort.

    • Sustained-Release (SR) Formulation: The sustained-release formulation ensures a steady release of Levosulpride throughout the day, maintaining its therapeutic effects over an extended period without the need for multiple doses.

  2. Rabeprazole (20mg):

    • Proton Pump Inhibitor (PPI): Rabeprazole effectively reduces stomach acid secretion, helping prevent and treat conditions like GERD, peptic ulcers, and gastritis.

    • Fast Acting: Rabeprazole provides quick relief from acid-related symptoms, offering a long-lasting effect in controlling stomach acid production.

Usage

RABISTRUM LS is used to manage a variety of gastrointestinal conditions. It should be used according to the doctor's instructions, as the dosage may vary based on the severity of the condition.

  1. Dosage:

    • The usual dosage of RABISTRUM LS is one tablet once a day, taken with or without food. However, the exact dosage and duration of treatment should be determined by a healthcare provider.

  2. How to Take:

    • RABISTRUM LS should be swallowed whole with a glass of water. Do not crush or chew the tablets as this may affect the prolonged-release mechanism of Levosulpride.

  3. Who Should Use:

    • RABISTRUM LS is suitable for individuals suffering from:

      • Gastroesophageal Reflux Disease (GERD)

      • Peptic Ulcers

      • Gastritis

      • Irritable Bowel Syndrome (IBS)

      • Delayed Gastric Emptying or Gastroparesis

    • It is important to consult a doctor before starting treatment to ensure the medication is appropriate for your condition.

FAQ Section

  1. What is the primary use of RABISTRUM LS?

    • RABISTRUM LS is primarily used to treat gastrointestinal conditions such as GERD, acid reflux, peptic ulcers, and IBS. The combination of Levosulpride and Rabeprazole works synergistically to relieve acid-related symptoms and improve gastrointestinal motility.

  2. Can I take RABISTRUM LS with other medications?

    • RABISTRUM LS may interact with certain medications, including other proton pump inhibitors (PPIs), anti-nausea drugs, or medications that affect gastrointestinal motility. Always inform your healthcare provider about all the medications you are currently taking.

  3. Can RABISTRUM LS be used during pregnancy?

    • RABISTRUM LS should only be used during pregnancy if prescribed by a healthcare provider, as there may be risks involved. Consult your doctor if you are pregnant or planning to become pregnant before using this medication.

  4. What are the common side effects of RABISTRUM LS?

    • Common side effects include headaches, dizziness, constipation, diarrhea, or abdominal discomfort. If any serious side effects, such as chest pain or severe gastrointestinal symptoms, occur, medical attention should be sought immediately.

  5. How long does it take for RABISTRUM LS to work?

    • The effects of Rabeprazole usually begin within a few hours of taking the medication, while the effects of Levosulpride may take a little longer, as it has a sustained-release formulation. Overall, patients should experience noticeable improvement in symptoms within a few days to a week.

Conclusion

RABISTRUM LS combines the powerful effects of Levosulpride and Rabeprazole to provide an effective treatment for gastrointestinal disorders. By enhancing gastrointestinal motility and reducing stomach acid production, it offers comprehensive relief from conditions like GERD, peptic ulcers, and IBS. Its sustained-release formulation ensures that the medication provides long-lasting effects, helping improve patient compliance and comfort.

For individuals struggling with digestive issues such as acid reflux or delayed gastric emptying, RABISTRUM LS represents a valuable option for treatment. However, it is essential to follow the prescribed dosage and consult a healthcare provider regularly to ensure that the medication remains safe and effective for individual needs. 

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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