R/C IPRATROP DUO 

Ipratropium (40mcg)& Levo -Salbutamol Sulphate (100mcg)

R/C IPRATROP DUO is a combination inhaler containing Ipratropium Bromide (40mcg) and Levo-Salbutamol Sulphate (100mcg). This medication is primarily used for the management of respiratory conditions such as Chronic Obstructive Pulmonary Disease (COPD) and asthma. The synergistic effect of these two active ingredients provides a comprehensive approach to bronchodilation, offering relief from symptoms like wheezing, shortness of breath, and chest tightness.

Active Ingredients and Their Functions

Ipratropium Bromide (40mcg)

Ipratropium Bromide is an anticholinergic bronchodilator. It works by blocking the action of acetylcholine on muscarinic receptors in the bronchial muscles. This inhibition leads to muscle relaxation and dilation of the airways, making it easier to breathe.

Levo-Salbutamol Sulphate (100mcg)

Levo-Salbutamol, also known as Levalbuterol, is a selective beta-2 adrenergic receptor agonist. This helps in quickly relieving bronchospasm and improving airflow.

Mechanism of Action

The combination of Ipratropium and Levo-Salbutamol works through different but complementary pathways to provide enhanced bronchodilation. While Ipratropium inhibits cholinergic-mediated bronchoconstriction, Levo-Salbutamol directly relaxes bronchial muscles through beta-2 receptor stimulation. This dual mechanism ensures a more effective and sustained relief from bronchospasm compared to monotherapy.

Indications

R/C IPRATROP DUO is indicated for:

• Asthma: Particularly in patients requiring both an anticholinergic and a beta-2 agonist for optimal control.

Dosage and Administration

Dosage

The recommended dosage for adults is typically one inhalation four times a day. However, the dosage may be adjusted based on the patient's response and the severity of the condition.

Administration

R/C IPRATROP DUO is administered via inhalation using a metered-dose inhaler (MDI). Patients should be instructed on the correct inhalation technique to ensure the medication reaches the lungs effectively.

Usage Instructions

1. Shake the Inhaler: Before each use, shake the inhaler well to mix the medication.
2. Prime the Inhaler: If using the inhaler for the first time or if it hasn't been used for a while, prime it by releasing a few sprays into the air.
3. Inhale Medication: Place the mouthpiece in the mouth, seal lips around it, and inhale deeply while pressing the canister to release the medication.
4. Hold Breath: Hold the breath for about 10 seconds to allow the medication to settle in the lungs.
5. Repeat if Necessary: If more than one inhalation is prescribed, wait for about a minute before taking the next puff, shaking the inhaler again before use.

Benefits

• Enhanced Bronchodilation: The combination of two bronchodilators provides superior bronchodilation compared to single-drug therapy.
• Quick Relief: Levo-Salbutamol acts rapidly, offering quick relief from acute bronchospasm.
• Prolonged Effect: Ipratropium provides a prolonged bronchodilatory effect, reducing the frequency of inhaler use.
• Improved Lung Function: Regular use can significantly improve lung function and overall respiratory health.

Side Effects

Like all medications, R/C IPRATROP DUO may cause side effects. However, not everyone experiences them. Common side effects include:

• Dry Mouth: Due to the anticholinergic effect of Ipratropium.
• Headache: A common side effect of beta-2 agonists.
• Nausea: Can occur but usually mild.
• Tachycardia: Increased heart rate due to Levo-Salbutamol.
• Tremors: Often associated with beta-2 agonists.
• Cough or Throat Irritation: From inhalation of the medication.

Precautions and Warnings

• Allergic Reactions: Avoid use if there is a known allergy to Ipratropium, Levo-Salbutamol, or any other ingredients in the inhaler.
• Cardiovascular Disorders: Use with caution in patients with heart conditions such as arrhythmias or hypertension.
• Hyperthyroidism: Patients with thyroid disorders should use this medication under close supervision.
• Glaucoma: The anticholinergic effect may worsen glaucoma; use with caution.
• Prostate Enlargement: May cause urinary retention in patients with benign prostatic hyperplasia.

Drug Interactions

R/C IPRATROP DUO can interact with other medications, which may alter its effects or increase the risk of adverse reactions. 

• Other Bronchodilators: Concurrent use can enhance the effects and side effects.
• Beta-Blockers: May reduce the effectiveness of Levo-Salbutamol.
• Diuretics: Increased risk of hypokalemia when used with beta-2 agonists.
• MAO Inhibitors: May potentiate the cardiovascular effects of Levo-Salbutamol.

Storage

• Moisture: Keep the inhaler in a dry place.
• Children: Store out of reach of children to prevent accidental use.

Conclusion

R/C IPRATROP DUO is a highly effective combination inhaler for managing COPD and asthma. By combining Ipratropium Bromide and Levo-Salbutamol Sulphate, it offers enhanced bronchodilation, rapid relief, and prolonged effects, making it an excellent choice for patients with respiratory conditions. Proper usage, adherence to prescribed dosages, and awareness of potential side effects and interactions are crucial for maximizing the benefits and minimizing risks. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology

For further information

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488

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