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ROXARIVABEN 20: Dosage, Benefits, and Side Effects Explained

Dec 20, 2024

Introduction

ROXARIVABEN 20 is a highly effective oral anticoagulant medication containing Rivaroxaban (20mg) as its active ingredient. Rivaroxaban belongs to the class of direct oral anticoagulants (DOACs) and is widely used for the prevention and treatment of thromboembolic disorders. By selectively inhibiting Factor Xa, it helps reduce the formation of harmful blood clots, offering a safer and more convenient alternative to traditional anticoagulants like warfarin.

This article provides an in-depth understanding of ROXARIVABEN 20, including its uses, benefits, mechanism of action, dosage guidelines, potential side effects, and precautions.

Key Ingredients

The primary component of ROXARIVABEN 20 is:

  • Rivaroxaban (20mg): A direct Factor Xa inhibitor that prevents blood clot formation by disrupting the coagulation cascade. It offers predictable pharmacokinetics, minimal drug interactions, and eliminates the need for routine blood monitoring, making it an innovative choice for anticoagulation therapy.

Uses of ROXARIVABEN 20

  1. Prevention of Stroke in Atrial Fibrillation
    Rivaroxaban (20mg) is prescribed for patients with non-valvular atrial fibrillation (AF) to lower the risk of stroke and systemic embolism. By preventing clot formation, it helps mitigate one of the most severe complications of AF.

  2. Treatment and Prevention of Deep Vein Thrombosis (DVT)
    ROXARIVABEN 20 is used to treat acute DVT and prevent its recurrence. DVT involves the formation of blood clots in the deep veins, often in the legs, which can lead to life-threatening complications if left untreated.

  3. Treatment and Prevention of Pulmonary Embolism (PE)
    Pulmonary embolism occurs when a clot travels to the lungs, blocking blood flow. Rivaroxaban (20mg) effectively treats PE and reduces the risk of future occurrences.

  4. Post-Surgical Thromboprophylaxis
    Patients undergoing orthopedic surgeries, such as hip or knee replacement, are at a high risk of developing blood clots. ROXARIVABEN 20 is commonly used as a preventive measure in such cases.

  5. Prevention of Cardiovascular Events in Coronary Artery Disease (CAD) and Peripheral Artery Disease (PAD)
    In combination with aspirin, Rivaroxaban (20mg) lowers the risk of major cardiovascular events, such as heart attacks and strokes, in patients with CAD or PAD.

How Does ROXARIVABEN 20 Work?

ROXARIVABEN 20, through its active ingredient Rivaroxaban (20mg), exerts its anticoagulant effect by directly inhibiting Factor Xa.

  1. Role of Factor Xa
    Factor Xa plays a central role in the blood coagulation process by converting prothrombin into thrombin, a key enzyme responsible for clot formation.

  2. Selective Inhibition
    Rivaroxaban (20mg) selectively binds to Factor Xa, blocking its activity and interrupting the coagulation cascade. This action reduces the formation of fibrin clots and prevents harmful blood clots from forming.

  3. Rapid Onset and Predictable Action
    Unlike traditional anticoagulants, ROXARIVABEN 20 has a rapid onset of action, predictable dosing, and does not require frequent monitoring, offering convenience and safety for patients.

Dosage and Administration

ROXARIVABEN 20 is available in tablet form and should be taken orally with food for optimal absorption. The dosage may vary depending on the medical condition:

  1. Non-Valvular Atrial Fibrillation

    • Standard Dose: 20 mg once daily with food.
    • For patients with impaired kidney function, the dose may be reduced to 15 mg once daily.
  2. Treatment of DVT and PE

    • Initial Phase: 15 mg twice daily for the first 21 days.
    • Maintenance Phase: 20 mg once daily with food.
  3. Post-Surgical Thromboprophylaxis

    • Typical Dose: 10 mg once daily for 10–35 days, depending on the type of surgery.
  4. CAD/PAD

    • Combination Therapy: 2.5 mg twice daily with low-dose aspirin.

Important: Always follow your doctor’s prescribed dosage and schedule.

Key Benefits of ROXARIVABEN 20

  1. Enhanced Safety Profile
    Compared to warfarin, Rivaroxaban (20mg) has a lower risk of major bleeding complications, particularly intracranial bleeding.

  2. Ease of Use
    No routine blood tests or dietary restrictions are required, offering patients greater freedom in managing their condition.

  3. Rapid and Predictable Effect
    Its quick onset and stable anticoagulant effect make it reliable for both acute and long-term therapy.

  4. Improved Patient Outcomes
    By effectively preventing clots, ROXARIVABEN 20 significantly reduces the risk of life-threatening complications like stroke, PE, and myocardial infarction.

  5. Wide Range of Applications
    Its versatility in treating and preventing thromboembolic disorders makes it a preferred choice among clinicians.

Potential Side Effects

While ROXARIVABEN 20 is generally well-tolerated, some patients may experience side effects. These include:

  • Common Side Effects

    • Minor bleeding (e.g., gums, nosebleeds)
    • Nausea
    • Headache
    • Fatigue
  • Serious Side Effects

    • Severe bleeding (e.g., gastrointestinal or intracranial)
    • Allergic reactions, such as rash or swelling
    • Liver function abnormalities

If you experience any unusual symptoms, such as prolonged bleeding, severe headache, or difficulty breathing, seek medical attention immediately.

Precautions and Warnings

  1. Kidney and Liver Impairment
    Patients with severe kidney or liver disease should use Rivaroxaban (20mg) with caution, as it may increase the risk of bleeding.

  2. Drug Interactions
    Inform your doctor about all medications you are taking, as some drugs (e.g., antifungals, antibiotics, NSAIDs) may interact with ROXARIVABEN 20.

  3. Pregnancy and Breastfeeding
    This medication is not recommended for use during pregnancy or breastfeeding unless deemed necessary by a healthcare provider.

  4. Surgical Procedures
    Inform your doctor if you are scheduled for surgery, as Rivaroxaban (20mg) may need to be discontinued temporarily.

Price in Indian Currency

The price of ROXARIVABEN 20 may vary based on the manufacturer, location, and pharmacy. On average, a strip of tablets ranges between ₹800 to ₹1500 in India. Check with local pharmacies or online platforms for the most accurate pricing.

Conclusion

ROXARIVABEN 20 is a revolutionary anticoagulant therapy that combines efficacy, safety, and convenience. With its active ingredient Rivaroxaban (20mg), it provides reliable prevention and treatment of thromboembolic disorders, offering a better quality of life to patients. Always use this medication under medical supervision and adhere to the prescribed dosage for optimal results. By addressing the needs of patients with a wide range of conditions, ROXARIVABEN 20 sets a high standard in anticoagulation therapy, making it an indispensable choice for modern healthcare. Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options. The company offers a wide range of healthcare products, catering to various medical needs, from rare disease treatments to essential healthcare products. Sterispharma's product range includes solutions for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. Medicines can be conveniently ordered via Our websites—Sterisonline, Sterisindia, and Sterispharma.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 7877551268, 7849827488

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