SAVELINER 400

Sevelamer (400mg)

"SAVELINER 400," is a medication commonly used to manage and control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis. This article will delve into the uses, dosage, side effects, and other essential aspects of SAVELINER 400, providing a comprehensive overview for patients and healthcare providers alike.

What is Sevelamer (SAVELINER 400)?

. It is particularly beneficial for patients with CKD on dialysis, who often struggle with hyperphosphatemia (high phosphate levels). By managing phosphorus levels, Sevelamer helps reduce the risk of cardiovascular complications and bone disorders associated with CKD.

Uses of SAVELINER 400

Managing Hyperphosphatemia

The primary use of SAVELINER 400 is to control hyperphosphatemia in patients with CKD on dialysis. Elevated phosphorus levels can lead to serious health problems, including cardiovascular disease, bone pain, and fractures. By binding to dietary phosphate, SAVELINER 400 helps prevent these complications.

Improving Quality of Life

By effectively managing phosphorus levels, SAVELINER 400 can improve the overall quality of life for CKD patients. It reduces the risk of complications and hospitalizations, allowing patients to maintain a more stable health status and adhere to their dialysis schedule without additional health concerns.

Dosage and Administration

Recommended Dosage

 Typically, the starting dose ranges from 800 to 1600 mg (2 to 4 tablets) taken three times daily with meals. Dosage adjustments are made based on regular monitoring of serum phosphorus levels.

Administration Guidelines

• Timing: SAVELINER 400 should be taken with meals to effectively bind dietary phosphate.
• Swallowing Tablets: Patients should swallow the tablets whole with water. Do not crush, chew, or break the tablets, as this can affect the medication's efficacy.
• Missed Dose: If a dose is missed, it should be taken with the next meal. 

Potential Side Effects

Common Side Effects

• Gastrointestinal Issues: The most common side effects of SAVELINER 400 include nausea, vomiting, diarrhea, and abdominal pain. 
• Constipation: Some patients may experience constipation, which can be alleviated by adjusting the dosage or incorporating dietary changes.

Serious Side Effects

• Intestinal Blockage: Although rare, there have been reports of intestinal blockage or perforation in patients taking Sevelamer. Patients should seek immediate medical attention if they experience severe abdominal pain, swelling, or difficulty passing stools.
• Allergic Reactions: Severe allergic reactions to SAVELINER 400 are uncommon but can occur. Patients should discontinue use and seek emergency medical help if these symptoms arise.

Precautions and Interactions

Precautions

• Swallowing Difficulties: Patients with swallowing difficulties or those at risk of choking should use caution when taking SAVELINER 400 tablets. An alternative form, such as powder, may be considered.
• Pregnancy and Breastfeeding: The safety of Sevelamer during pregnancy and breastfeeding is not well-established. Pregnant or breastfeeding women should consult their healthcare provider before using SAVELINER 400.

Drug Interactions

• Medications: Sevelamer may interact with certain medications, including antiarrhythmic drugs, antiepileptics, and antibiotics. 
• Vitamins and Minerals: Sevelamer can affect the absorption of fat-soluble vitamins (A, D, E, and K) and other nutrients. 

Monitoring and Follow-Up

Regular Monitoring

Patients on SAVELINER 400 should undergo regular monitoring of serum phosphorus, calcium, and parathyroid hormone (PTH) levels. This helps ensure the medication's effectiveness and allows for timely adjustments to the dosage.

Follow-Up Visits

Regular follow-up visits with a healthcare provider are essential for patients taking SAVELINER 400. These visits help monitor the patient's response to treatment, manage any side effects, and make necessary adjustments to the treatment plan.

Patient Education and Support

Dietary Counseling

In addition to medication, dietary management plays a crucial role in controlling phosphorus levels. Patients should receive dietary counseling to limit high-phosphorus foods, such as dairy products, nuts, seeds, and certain meats.

Adherence to Treatment

Adherence to the prescribed treatment regimen is vital for the effectiveness of SAVELINER 400. Patients should be educated on the importance of taking the medication as directed and attending all scheduled follow-up appointments.

Conclusion

SAVELINER 400 (Sevelamer 400mg) is a valuable medication for managing hyperphosphatemia in patients with chronic kidney disease on dialysis. By effectively controlling serum phosphorus levels, it helps reduce the risk of serious complications and improve the overall quality of life for patients. Proper dosage, regular monitoring, and patient education are essential components of successful treatment with SAVELINER 400. Patients should work closely with their healthcare providers to ensure optimal outcomes and address any concerns related to their treatment regimen. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology,Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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