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SAVELINER 800 & Sevelamer (800mg).:Tablet- Uses, Side Effects, Dosage, Mechanism of action...

Jul 22, 2024

SAVELINER 800 

Sevelamer (800mg)

SAVELINER 800 contains Sevelamer(800 mg), a phosphate binder used primarily to manage hyperphosphatemia in patients with chronic kidney disease (CKD) on dialysis. This medication is crucial in preventing complications associated with elevated phosphate levels, such as cardiovascular diseases and bone disorders. In this article, we will delve into the uses, dosage, side effects, precautions, and other essential aspects of SAVELINER 800.

Uses of SAVELINER 800

Management of Hyperphosphatemia

Hyperphosphatemia, or elevated phosphate levels in the blood, is a common issue in patients with CKD. The kidneys' impaired ability to filter and remove phosphate leads to its accumulation. SAVELINER 800 helps control these levels by binding to phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream.

Prevention of Cardiovascular Complications

High phosphate levels are linked to an increased risk of cardiovascular diseases. By reducing phosphate absorption, SAVELINER 800 helps mitigate these risks, contributing to better cardiovascular health in CKD patients.

Bone Health

Elevated phosphate can lead to mineral and bone disorders in CKD patients. SAVELINER 800 helps maintain healthy phosphate levels, promoting better bone health and reducing the risk of bone-related complications.

Dosage and Administration

Standard Dosage

The typical starting dose of SAVELINER 800 is one tablet three times a day with meals. However, the exact dosage may vary depending on the patient's serum phosphate levels and response to treatment. 

Administration Guidelines

  • With Meals: Take SAVELINER 800 with meals to ensure optimal binding of dietary phosphate.
  • Swallow Whole: Swallow them whole with water.
  • Regular Monitoring: Regular blood tests are necessary to monitor phosphate levels and adjust the dosage accordingly.

Side Effects

Common Side Effects

  • Gastrointestinal Issues: These symptoms are usually mild and tend to resolve over time.
  • Indigestion: Indigestion and flatulence can occur but are generally manageable with dietary adjustments and over-the-counter remedies.

Serious Side Effects

  • Bowel Obstruction: In rare cases, SAVELINER 800 can cause bowel obstruction. Seek immediate medical attention if you experience severe abdominal pain, vomiting, or inability to pass stools.
  • Hypocalcemia: This medication can lead to low calcium levels in the blood, especially if dietary calcium intake is insufficient. Symptoms include muscle cramps, spasms, or tingling in the fingers.

Precautions and Warnings

Allergic Reactions

Patients with a known allergy to sevelamer or any of its components should avoid taking SAVELINER 800.

Medical Conditions

  • Gastrointestinal Disorders: Patients with a history of bowel obstruction, severe constipation, or other gastrointestinal motility disorders should use SAVELINER 800 with caution.
  • Swallowing Difficulties: Individuals with difficulty swallowing tablets should consult their healthcare provider, as sevelamer tablets need to be swallowed whole.

Drug Interactions

 Inform your healthcare provider about all the medications you are taking, including:

  • Antibiotics: Such as ciprofloxacin and mycophenolate mofetil. These should be taken at least one hour before or three hours after SAVELINER 800.
  • Antiarrhythmics: Such as amiodarone, which may have altered absorption when taken with sevelamer.

Special Populations

Pregnant and Breastfeeding Women

The safety of sevelamer in pregnant and breastfeeding women is not well-established. Consult your healthcare provider before using SAVELINER 800 if you are pregnant, planning to become pregnant, or breastfeeding.

Elderly Patients

Elderly patients may be more susceptible to the side effects of SAVELINER 800. Regular monitoring and dose adjustments are essential to minimize risks.

Lifestyle and Dietary Considerations

Phosphate-Restricted Diet

While taking SAVELINER 800, it is important to adhere to a phosphate-restricted diet. Foods high in phosphate, such as dairy products, nuts, seeds, and certain beverages, should be limited.

Calcium and Vitamin D Supplementation

Since sevelamer can affect calcium levels, your healthcare provider may recommend calcium and vitamin D supplements to ensure adequate intake and prevent deficiencies.

Conclusion

SAVELINER 800 (Sevelamer 800mg) is an effective phosphate binder crucial for managing hyperphosphatemia in CKD patients. By reducing phosphate absorption, it helps prevent complications related to elevated phosphate levels, such as cardiovascular diseases and bone disorders. Adhering to the prescribed dosage, monitoring blood phosphate levels, and maintaining a phosphate-restricted diet are essential for optimal results. Always consult your healthcare provider for personalized medical advice and report any side effects or concerns promptly. With proper use and monitoring, SAVELINER 800 can significantly improve the quality of life for CKD patients, helping them manage their condition more effectively. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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