SAVELINER 800 

Sevelamer (800mg)

SAVELINER 800, containing Sevelamer (800mg), is a medication widely prescribed to patients with chronic kidney disease (CKD) to help control phosphorus levels in the blood. High phosphorus levels can lead to bone and heart problems in CKD patients. This comprehensive guide explores the uses, dosage, side effects, and other critical aspects of Sevelamer.

Uses of SAVELINER 800

1. Managing Hyperphosphatemia

The primary use of SAVELINER 800 is to manage hyperphosphatemia in patients with chronic kidney disease (CKD) on dialysis. Elevated phosphorus levels can cause severe complications, including bone and cardiovascular diseases.

2. Preventing Calcification

By controlling phosphorus levels, Sevelamer helps prevent vascular calcification, which can reduce the risk of heart disease in CKD patients.

Dosage and Administration

1. Standard Dosage

The typical starting dose of Sevelamer for adults is 800 to 1600 mg taken with meals. The exact dosage depends on the patient’s serum phosphorus level.

2. Administration Tips

• With Meals: To maximize its effectiveness, SAVELINER 800 should be taken with meals. This timing allows the medication to bind dietary phosphate efficiently.
• Consistency: Maintaining a consistent schedule for taking Sevelamer helps in better management of phosphorus levels.
• Dosage Adjustment: Regular monitoring of phosphorus levels is crucial. Based on these levels, the dosage may need adjustment.

Mechanism of Action

Sevelamer works by binding phosphate in the gastrointestinal tract, which prevents its absorption into the bloodstream. This binding occurs through ionic and hydrogen bonding, which makes the phosphate non-absorbable and excretes it through feces.

Side Effects

While SAVELINER 800 is generally well-tolerated, some patients may experience side effects. Common side effects include:

1. Gastrointestinal Issues

• Nausea: Some patients may feel nauseous after taking the medication.
• Vomiting: Vomiting can occur, particularly if the medication is not taken with food.
• Diarrhea or Constipation: These are common gastrointestinal side effects.

2. Metabolic Concerns

• Hypocalcemia: In rare cases, Sevelamer may lead to low blood calcium levels, necessitating close monitoring.

Precautions and Warnings

1. Medical History

Before starting SAVELINER 800, inform your healthcare provider about your medical history, especially if you have any gastrointestinal disorders, swallowing problems, or a history of bowel obstruction.

2. Drug Interactions

Sevelamer can interact with other medications. To avoid interactions:

• Space Out Medications: Take other medications either 1 hour before or 3 hours after taking Sevelamer.
• Consult Your Doctor: Always consult your healthcare provider before starting any new medication.

3. Pregnancy and Breastfeeding

• Pregnancy: There is limited data on the use of Sevelamer in pregnant women.
• Breastfeeding: It is unknown if Sevelamer passes into breast milk. Consult your doctor before breastfeeding.

Benefits of SAVELINER 800

1. Effective Phosphate Control

Sevelamer is effective in reducing serum phosphorus levels, which helps prevent the complications associated with hyperphosphatemia.

2. Non-Calcium Based

Unlike some phosphate binders, Sevelamer does not contain calcium, which helps avoid the risk of hypercalcemia (high calcium levels).

How to Store SAVELINER 800

• Keep Out of Reach of Children: Ensure the medication is stored safely out of the reach of children and pets.
• Original Packaging: Keep the medication in its original packaging until ready to use.

Frequently Asked Questions

1. Can SAVELINER 800 be taken with other phosphate binders?

Yes, in some cases, your healthcare provider may recommend using Sevelamer in combination with other phosphate binders for optimal control of phosphorus levels.

3. Are there any dietary restrictions while taking SAVELINER 800?

While taking Sevelamer, it’s advisable to follow a low-phosphorus diet as recommended by your healthcare provider. This helps in managing phosphorus levels effectively.

Conclusion

SAVELINER 800 (Sevelamer 800mg) is a critical medication for managing hyperphosphatemia in patients with chronic kidney disease on dialysis. Its ability to control serum phosphorus levels without causing hypercalcemia makes it a valuable treatment option. While generally safe and well-tolerated, it’s important to follow the prescribed dosage and take necessary precautions to avoid potential side effects.  By understanding the uses, dosage, side effects, and precautions of SAVELINER 800, patients can effectively manage their phosphorus levels and improve their overall health. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology,Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology. 

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