Introduction

STYLECYSTIN 400 IV INJECTION is a pharmaceutical formulation containing Acetylcysteine Injection BP 200 ml, primarily used as a mucolytic agent and antidote for paracetamol poisoning. Acetylcysteine is a derivative of the amino acid L-cysteine, known for its potent antioxidant and mucolytic properties. This injection plays a crucial role in managing respiratory conditions characterized by excessive mucus production and in treating acetaminophen overdose.

Key Ingredients

• Acetylcysteine Injection BP 200 ml – The active ingredient that works by breaking down mucus in the airways and replenishing glutathione levels in the liver.

• Sterile Water for Injection – A solvent to ensure safe and effective delivery of the medication intravenously.

Key Benefits

1. Mucolytic Properties

STYLECYSTIN 400 IV INJECTION acts as a mucolytic agent, helping to dissolve and loosen thick mucus in the lungs, making it easier to clear secretions in conditions like:

• Chronic obstructive pulmonary disease (COPD)

• Bronchitis

• Cystic fibrosis

• Pneumonia

2. Treatment for Paracetamol Overdose

One of the most critical applications of Acetylcysteine Injection BP 200 ml is as an antidote for paracetamol (acetaminophen) poisoning. By replenishing glutathione levels, it protects the liver from toxic damage caused by excessive doses of paracetamol.

3. Antioxidant Properties

Acetylcysteine is a powerful antioxidant, which helps neutralize harmful free radicals and prevent oxidative damage, making it beneficial in conditions like:

• Lung fibrosis

• Neurological disorders

• Cardiovascular diseases

4. Anti-inflammatory Effects

This injection exhibits anti-inflammatory properties, reducing lung inflammation and improving respiratory function in conditions like asthma and COPD.

How Does It Work?

STYLECYSTIN 400 IV INJECTION works through the following mechanisms:

• Breaks Disulfide Bonds – It disrupts the structure of mucus, reducing its viscosity and aiding in easier clearance from the airways.

• Replenishes Glutathione – In paracetamol overdose, Acetylcysteine restores glutathione levels in the liver, preventing hepatotoxicity.

• Reduces Oxidative Stress – By acting as a precursor to glutathione, it neutralizes reactive oxygen species (ROS) and minimizes cell damage.

Directions for Use

• Administered intravenously (IV) under medical supervision.

• Dosage for paracetamol overdose:

  • Initial dose: 150 mg/kg infused over 1 hour

  • Followed by 50 mg/kg over 4 hours

  • Then 100 mg/kg over 16 hours

• Dosage for mucolytic therapy:

  • Typically, a single IV dose of 600 mg to 1200 mg per day, depending on the severity of the condition.

• Always follow the doctor's instructions for optimal results.

Side Effects

While STYLECYSTIN 400 IV INJECTION is generally well tolerated, some individuals may experience side effects, including:

Common Side Effects:

• Nausea and vomiting

• Skin rash or urticaria

• Flushing or warmth sensation

Serious Side Effects:

• Anaphylactoid reactions (including swelling, shortness of breath, and hypotension)

• Bronchospasm in asthmatic patients

• Liver enzyme abnormalities

• Hypersensitivity reactions

If any severe symptoms occur, immediate medical attention is necessary.

Precautions & Warnings

• Allergy Alert – Avoid use if allergic to Acetylcysteine or any of its components.

• Asthma Patients – Use with caution in individuals with a history of bronchospasm or asthma.

• Pregnancy & Lactation – Should be used under medical supervision in pregnant or breastfeeding women.

• Kidney & Liver Disorders – Requires dose adjustments in patients with hepatic or renal impairment.

Drug Interactions

STYLECYSTIN 400 IV INJECTION may interact with:

• Activated Charcoal – May reduce the effectiveness of Acetylcysteine.

• Nitroglycerin – Can lead to excessive vasodilation and hypotension.

• Antibiotics (Tetracycline, Aminoglycosides, Penicillins) – Should not be mixed in the same IV line due to incompatibility.

• Carbamazepine & Warfarin – May affect their metabolism and efficacy.

Storage Guidelines

• Store at controlled room temperature (15-25°C).

• Protect from light and moisture.

• Use within the recommended period after opening.

• Do not freeze.

Price & Availability in India

The cost of STYLECYSTIN 400 IV INJECTION varies based on the manufacturer and location. In India, the approximate price range is ₹500-₹1500 per 200 ml vial. Always check with local pharmacies or online platforms for current pricing and availability.

Conclusion

STYLECYSTIN 400 IV INJECTION, containing Acetylcysteine Injection BP 200 ml, is an essential medication for treating paracetamol overdose, respiratory conditions, and oxidative stress-related disorders. Its mucolytic, antioxidant, and hepatoprotective properties make it highly effective in various medical applications. Always consult a healthcare professional for proper dosage, administration, and monitoring to ensure optimal therapeutic benefits while minimizing risks.

About The Author

STERIS HEALTHCARE PVT LTD

Steris Healthcare Pvt Ltd, known as Sterispharma, was founded in February 2018 by a team of experienced professionals in the pharmaceutical industry. Headquartered in Navi Mumbai, the company holds certifications from WHO, GMP, and ISO, reflecting its dedication to maintaining high standards of quality and safety. Sterispharma’s mission is to provide affordable, high-quality medications across India, strictly adhering to WHO guidelines. With the convenience of an online pharmacy, customers can easily order medicines with home delivery options.

For further information 

Email: info@sterispharma.com / contact@sterispharma.com

Call/WhatsApp: 8209542042 , 8824175417

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