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Sulfasalazine Tablet (500mg) - Extended Release, Uses, & Side Effects.

Jul 24, 2024

SULFASALAZ 500 15'S 

Sulfasalazine Tablet (500mg)

Introduction

SULFASALAZ 500 15'S, featuring Sulfasalazine 500mg, is a medication widely prescribed for inflammatory bowel diseases (IBD) and rheumatoid arthritis (RA). This drug works through a combination of sulfapyridine and 5-aminosalicylic acid (5-ASA), providing both anti-inflammatory and immunosuppressive effects. It is a cornerstone treatment for reducing inflammation and managing symptoms in patients with conditions like ulcerative colitis and rheumatoid arthritis.

Uses

Sulfasalazine is indicated for:

  • Ulcerative Colitis: Effective in inducing and maintaining remission of mild to moderate ulcerative colitis.
  • Rheumatoid Arthritis: Used as a disease-modifying antirheumatic drug (DMARD) to reduce joint inflammation, pain, and progression of the disease.
  • Crohn's Disease: Helps control symptoms and inflammation in mild to moderate Crohn's disease.

Dosage

The appropriate dosage of SULFASALAZ 500 15'S varies depending on the specific condition and patient response:

  • For Ulcerative Colitis:
    • Initial Dose: Typically starts at 500mg to 1g, taken 2 to 4 times daily.
    • Maintenance Dose: 500mg to 1g, taken 2 to 4 times daily, to prevent relapse.
  • For Rheumatoid Arthritis:
    • Initial Dose: Begins at 500mg daily, with gradual increments up to 1g, taken 2 to 3 times daily.
    • Maintenance Dose: 2g to 3g daily, divided into multiple doses, for ongoing management.
  • For Crohn's Disease:
    • Initial Dose: 500mg to 1g, taken 2 to 4 times daily.
    • Maintenance Dose: Adjusted based on efficacy and tolerance, usually 2g to 3g daily.

Side Effects

Common side effects include:

  • Gastrointestinal Disturbances: Nausea, vomiting, loss of appetite.
  • Headache: Commonly reported, especially at higher doses.
  • Skin Reactions: Rash, itching, and increased sensitivity to sunlight.
  • Oligospermia: Temporary reduction in sperm count, reversible upon discontinuation.
  • Discoloration: Orange-yellow coloration of urine and skin.

Serious side effects may involve:

  • Hepatotoxicity: Liver enzyme elevations, jaundice, hepatitis.
  • Severe Allergic Reactions: Angioedema, difficulty breathing, severe rash.
  • Renal Impairment: Rare cases of kidney damage, including interstitial nephritis.

Price

The cost of SULFASALAZ 500 15'S can vary, influenced by factors such as location, pharmacy, and insurance. Generally, a pack of 15 tablets is priced between INR 200 and INR 400. Patients should verify the exact pricing with local pharmacies or through online drug stores.

Conclusion

SULFASALAZ 500 15'S (Sulfasalazine Tablet, 500mg) provides significant benefits for patients with inflammatory bowel diseases and rheumatoid arthritis. Its combined anti-inflammatory and immunomodulatory effects make it a vital medication for managing these chronic conditions. However, it requires careful usage under medical supervision due to potential side effects. Adhering to the prescribed dosage and regular medical check-ups ensures effective and safe treatment outcomes. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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