TICAGRACE 60 

Ticagrelor (60mg)

Ticagrelor (60 mg), marketed under the brand name TICAGRACE 60, is an essential medication in the field of cardiovascular health. It is commonly used to reduce the risk of heart attack and stroke in patients with a history of acute coronary syndrome (ACS) or those who have undergone coronary artery bypass grafting (CABG). As a member of the antiplatelet drug class, Ticagrelor plays a crucial role in preventing blood clots that could lead to severe cardiovascular events.

What is Ticagrelor?

Ticagrelor is a potent oral antiplatelet medication that works by inhibiting platelet activation and aggregation. This reversible binding means that Ticagrelor’s effects can be adjusted if needed, offering a flexible approach to managing patients' cardiovascular risk.

How Ticagrelor (60mg) Works

Mechanism of Action

Ticagrelor targets the P2Y12 receptor on platelets, a crucial component in the clotting process. By blocking this receptor, Ticagrelor prevents the activation of platelets and their subsequent aggregation. This action significantly reduces the likelihood of clot formation, which is particularly beneficial for patients at high risk of cardiovascular events.

Dosage and Administration

TICAGRACE 60 contains Ticagrelor in a 60mg dose. The typical recommended dosage is one 60mg tablet taken twice daily, usually in combination with aspirin. The specific dosage and duration of treatment may vary based on individual patient factors and the underlying condition being treated.

Onset of Action

Ticagrelor begins to work within a few hours of administration. Its maximum antiplatelet effect is generally observed within 1-3 hours of ingestion. The reversible nature of its binding means that platelet function can return to baseline relatively quickly once the medication is discontinued.

Clinical Uses of Ticagrelor (60mg)

Acute Coronary Syndrome (ACS)

In patients with ACS, Ticagrelor is used to reduce the risk of major cardiovascular events such as heart attack and stroke. ACS encompasses conditions like unstable angina and myocardial infarction, where immediate and effective antiplatelet therapy is crucial for improving outcomes.

Post-Coronary Artery Bypass Grafting (CABG)

Following CABG, Ticagrelor helps in preventing the formation of blood clots that could lead to graft occlusion or other complications. It is often prescribed in conjunction with aspirin to maximize therapeutic benefit and reduce the risk of adverse cardiovascular events.

Benefits of TICAGRACE 60

Reduced Risk of Cardiovascular Events

Clinical studies have demonstrated that Ticagrelor is highly effective in reducing the risk of major cardiovascular events compared to other antiplatelet agents. Its rapid onset and reversible action make it a valuable tool in managing patients with high cardiovascular risk.

Flexible Dosing

The reversible nature of Ticagrelor allows for flexible dosing adjustments. This feature is particularly useful in managing patients who may require changes in their treatment regimen based on their clinical condition or response to the medication.

Improved Patient Outcomes

Patients taking Ticagrelor have shown improved outcomes in terms of reduced incidence of heart attack and stroke. This medication has been associated with better long-term cardiovascular health and a lower rate of recurrent events in patients with a history of ACS.

Side Effects and Precautions

Common Side Effects

Ticagrelor may cause side effects, although not everyone will experience them. Common side effects include:

• Bleeding: As with any antiplatelet medication, there is an increased risk of bleeding. This can range from minor bruising to more severe bleeding complications.
• Shortness of Breath: Some patients may experience shortness of breath or dyspnea, which should be reported to a healthcare provider.

Serious Side Effects

In rare cases, Ticagrelor may lead to more severe side effects such as:

• Severe Bleeding: This includes gastrointestinal bleeding or bleeding in the brain. Immediate medical attention is required if symptoms of severe bleeding occur.
• Bradycardia: Ticagrelor can cause a slower heart rate in some patients. Monitoring and dose adjustments may be necessary for those with pre-existing heart conditions.

Drug Interactions

Ticagrelor can interact with other medications, potentially altering its effectiveness or increasing the risk of side effects. Important drug interactions to consider include:

• Anticoagulants: Concurrent use with anticoagulants like warfarin or direct oral anticoagulants can increase bleeding risk.
• Certain Antifungals and Antibiotics: Medications such as ketoconazole or clarithromycin may affect Ticagrelor levels and efficacy.

Patient Considerations

Monitoring

Patients on Ticagrelor should be regularly monitored for signs of bleeding or other adverse effects. Regular follow-up appointments with a healthcare provider are essential to ensure the medication is working effectively and to make any necessary adjustments to the treatment plan.

Lifestyle Modifications

While Ticagrelor helps manage cardiovascular risk, lifestyle modifications are also important. Patients should adopt a heart-healthy diet, engage in regular physical activity, and avoid smoking to enhance overall cardiovascular health.

Conclusion

TICAGRACE 60, containing 60mg of Ticagrelor, is a crucial medication for managing patients at high risk of cardiovascular events. Its potent antiplatelet effects, flexible dosing, and proven benefits make it a valuable tool in modern cardiovascular therapy. However, careful monitoring and consideration of potential side effects and drug interactions are essential to optimize treatment outcomes. By combining Ticagrelor with lifestyle modifications and regular medical supervision, patients can effectively reduce their risk of serious cardiovascular complications and improve their long-term health. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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