TMOZOLMIDE 250

Temozolomide (250 mg)

TMOZOLMIDE 250, containing Temozolomide 250mg, offers substantial therapeutic benefits for patients dealing with aggressive brain tumors. This article explores the uses, dosage, side effects, price, and other essential considerations regarding TMOZOLMIDE 250.

Introduction to Temozolomide

Temozolomide is an alkylating agent that works by damaging the DNA of cancer cells, inhibiting their replication and leading to cell death. Approved by the FDA in 1999, Temozolomide has become an essential treatment for malignant brain tumors, providing hope for patients facing these challenging conditions.

Uses of TMOZOLMIDE 250

Glioblastoma Multiforme

TMOZOLMIDE 250 is widely used in treating glioblastoma multiforme (GBM), one of the most aggressive and common primary brain tumors in adults. It is often used in combination with radiation therapy to enhance its effectiveness and improve patient outcomes.

Anaplastic Astrocytoma

Temozolomide is also indicated for treating anaplastic astrocytoma, a high-grade glioma. TMOZOLMIDE 250 helps manage this malignant tumor by slowing its growth and progression.

Other Brain Tumors

In some cases, TMOZOLMIDE 250 may be used off-label to treat other types of brain tumors and metastatic cancers that have spread to the brain, offering hope to patients with limited treatment options.

Dosage and Administration

The dosage of TMOZOLMIDE 250 varies based on the patient’s condition, treatment phase, and response to therapy. General guidelines for its administration include:

• Standard Regimen: For newly diagnosed glioblastoma multiforme, the initial dosage typically involves 75 mg/m² per day for 42 days (concurrent with radiotherapy), followed by maintenance therapy of 150-200 mg/m² per day for 5 days in a 28-day cycle. TMOZOLMIDE 250 may be used as part of this regimen.
• Recurrent Glioma: For recurrent gliomas, the dosage may start at 150 mg/m² per day for 5 days in a 28-day cycle, increasing to 200 mg/m² per day if tolerated. TMOZOLMIDE 250 can be adjusted to meet these dosing requirements.

Administration:

• TMOZOLMIDE 250 should be taken on an empty stomach, ideally at least one hour before or two hours after a meal, to improve absorption and reduce nausea.
• Consistency in the timing of the dose each day is crucial to maintain stable blood levels of the medication.

Side Effects of TMOZOLMIDE 250

While TMOZOLMIDE 250 is effective in treating brain tumors, it is associated with several potential side effects. Patients should be closely monitored for any adverse reactions.

Common Side Effects

• Nausea and Vomiting: These are the most common side effects and can often be managed with anti-nausea medications.
• Fatigue: Patients may experience significant tiredness and lack of energy.
• Headaches: Headaches are a common complaint, particularly in patients with brain tumors.
• Constipation: This can be managed with dietary adjustments and medications.
• Loss of Appetite: A decrease in appetite may occur, potentially leading to weight loss.

Serious Side Effects

• Myelosuppression: This includes neutropenia (low white blood cell count), thrombocytopenia (low platelet count), and anemia, increasing the risk of infections and bleeding.
• Liver Toxicity: Regular monitoring of liver function is necessary as Temozolomide can cause liver enzyme elevations.
• Allergic Reactions: Severe allergic reactions are rare but can occur and require immediate medical attention.

Price of TMOZOLMIDE 250

The cost of TMOZOLMIDE 250 can vary based on factors such as region, pharmacy, and insurance coverage. On average, the price for a month's supply (depending on dosage) can range from ₹30,000 to ₹60,000 in India. Patients should consult their healthcare providers and local pharmacies for the most accurate pricing information.

Conclusion

TMOZOLMIDE 250, containing Temozolomide 250mg, is a crucial medication in the treatment of aggressive brain tumors such as glioblastoma multiforme and anaplastic astrocytoma. Despite its potential side effects, its role in improving patient outcomes in these challenging conditions is invaluable. Patients should work closely with their healthcare providers to monitor their treatment and manage any adverse effects effectively. Always consult your doctor for personalized medical advice and to understand the best way to incorporate TMOZOLMIDE 250 into your treatment plan.

Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

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