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TOPERITIME EX : Tolperisone Hcl (150mg) & Etoricoxib (60mg) Tab Overview....

Aug 07, 2024

TOPERITIME EX 

Tolperisone Hcl (150mg) & Etoricoxib (60mg) Tab

TOPERITIME EX is a pharmaceutical combination that merges two potent compounds—Tolperisone Hcl and Etoricoxib—to address musculoskeletal discomfort and pain. This innovative medication is designed to offer relief from acute and chronic conditions where pain management and muscle relaxation are crucial. By understanding how each component contributes to the overall efficacy of TOPERITIME EX, patients and healthcare providers can make informed decisions regarding its use.

What is Tolperisone Hcl?

Tolperisone Hcl is a muscle relaxant that works centrally within the nervous system. It is effective in relieving muscle spasticity and associated pain without causing significant sedation, which is common in many other muscle relaxants. Tolperisone achieves muscle relaxation by acting on the spinal cord and brain, reducing the transmission of nerve impulses that cause muscle stiffness and spasm.

Mechanism of Action

Tolperisone’s action is primarily through its ability to modulate the activity of the central nervous system. It inhibits the excessive neural excitability that leads to muscle spasm, providing relief from painful muscle contractions. This makes it especially useful in conditions such as back pain, spasticity related to neurological disorders, and musculoskeletal injuries.

Uses

Tolperisone Hcl is prescribed for:

  • Relief from acute muscle spasm.
  • Management of chronic spastic conditions.
  • Treatment of musculoskeletal pain related to injuries or strain.

Dosage

Typically, the dosage of Tolperisone Hcl is adjusted based on the patient's condition and response to treatment. Commonly, the recommended dose is 150mg to 300mg per day, divided into two or three doses. 

Side Effects

Potential side effects of Tolperisone Hcl include dizziness, drowsiness, nausea, and gastrointestinal disturbances. In rare cases, patients may experience allergic reactions or liver enzyme abnormalities. If any severe side effects occur, it is important to consult a healthcare professional promptly.

What is Etoricoxib?

Etoricoxib is a nonsteroidal anti-inflammatory drug (NSAID) belonging to the COX-2 inhibitor class. It provides effective pain relief and reduces inflammation by selectively inhibiting the cyclooxygenase-2 enzyme (COX-2), which is involved in the inflammatory process. This selective inhibition minimizes gastrointestinal side effects compared to traditional NSAIDs.

Mechanism of Action

Etoricoxib reduces pain and inflammation by blocking COX-2, an enzyme responsible for the production of prostaglandins—chemicals that mediate inflammation and pain. By inhibiting COX-2, Etoricoxib lowers the levels of these inflammatory mediators, thereby alleviating pain and reducing swelling.

Uses

Etoricoxib is commonly used for:

  • Relief of osteoarthritis pain.
  • Management of rheumatoid arthritis symptoms.
  • Treatment of acute pain conditions such as dental pain or postoperative pain.

Dosage

For Etoricoxib, the standard dosage is 60mg to 120mg per day, depending on the severity of the condition being treated. The exact dosage should be determined by a healthcare provider based on individual patient needs and response to the medication.

Side Effects

Possible side effects of Etoricoxib include gastrointestinal issues such as nausea and dyspepsia, cardiovascular events, and renal impairment.Patients should be monitored regularly for any adverse effects during treatment.

Benefits of Combining Tolperisone Hcl and Etoricoxib

The combination of Tolperisone Hcl and Etoricoxib in TOPERITIME EX provides a synergistic effect for managing pain and muscle spasm. Tolperisone’s muscle relaxant properties complement Etoricoxib’s anti-inflammatory and analgesic effects. This dual approach addresses both the muscle spasm and associated pain, leading to more comprehensive relief.

Enhanced Pain Relief

By combining a muscle relaxant with an NSAID, TOPERITIME EX offers effective pain relief through multiple mechanisms. This combination can be particularly beneficial in treating conditions that involve both muscle spasms and inflammation, such as in cases of acute back pain or post-surgical recovery.

Improved Patient Compliance

The use of a single combination tablet simplifies the treatment regimen, potentially improving patient compliance. Instead of taking multiple medications, patients can achieve better management of their symptoms with one combined therapy.

Dosage and Administration

TOPERITIME EX should be administered as directed by a healthcare provider. The typical dosage involves taking one tablet daily or as prescribed. 

Conclusion

TOPERITIME EX, combining Tolperisone Hcl (150mg) and Etoricoxib (60mg), is a powerful medication for managing both muscle spasm and associated pain. Its dual-action formula offers significant benefits for individuals suffering from musculoskeletal discomfort and inflammatory conditions.  As with any medication, it is essential to use TOPERITIME EX under the guidance of a healthcare professional to ensure its safety and effectiveness. Regular monitoring and adherence to prescribed guidelines will help in achieving optimal therapeutic outcomes. Steris Healthcare Pvt Ltd, operating as Sterispharma since its founding by expert professionals in the pharmaceutical industry in February 2018, is based in Navi Mumbai. The company is certified by WHO, GMP, and ISO, emphasizing its commitment to quality and safety. Sterispharma focuses on providing high-quality drugs at affordable prices throughout India, adhering strictly to WHO guidelines. Offering the convenience of an online pharmacy, customers can easily purchase medicines with home delivery options available. Sterispharma's mission is to supply a broad range of healthcare products to meet the diverse needs of the medical community. From advanced treatments and medications for rare conditions to essential health necessities, Sterispharma aims to serve the extensive demands of the healthcare industry. You can order medicines from Sterispharma through their websites, sterisonline and sterispharma. Their extensive product lineup includes treatments for Cardiology, Asthma, Respiratory Issues, Nasal Conditions, Diabetes, Endocrinology, Gastroenterology, Orthopedics, Anti-infectives/Antibiotics, General Medicine, Urology, Neurology, Nephrology, Oncology, Gynecology, Pediatrics, Dental Care, and Dermatology.

For further information 

Email: info@sterispharma.com /  contact@sterispharma.com

Call/WhatsApp:  7877551268, 7849827488 

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